Faktu
Faktu Uses, Dosage, Side Effects, Food Interaction and all others data.
Cinchocaine prevents or diminishes nerve impulse conduction near to the site of admin. It also has membrane-stabilising effect owing to decrease of permeability of the nerve cell to sodium ions.
Dibucaine is an amide-type local anesthetic, similar to lidocaine.
| Trade Name | Faktu |
| Generic | Cinchocaine + Policresulen |
| Weight | 10mg, 50mg, 10mg. |
| Type | Ointment |
| Therapeutic Class | |
| Manufacturer | Ranbaxy Laboratories (sun Pharma), Pharos Indonesia |
| Available Country | India, Indonesia |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Cinchocaine is used for Surface anaesthesia, Haemorrhoids
Faktu is also used to associated treatment for these conditions: Hemorrhoids, Pruritis of the skin, Pruritus Ani, Skin IrritationTrichomonas Vaginalis Infection, Vaginal Infections, Antisepsis, Oral wound cleansing
How Faktu works
Local anesthetics block both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions through sodium channel inhibition. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.
Dosage
Faktu dosage
Surface anesthesia: Use up to 1% cream or ointment topically for adult or as directed by physician.
Side Effects
Restlessness; excitement; nervousness; paraesthesias; dizziness; tinnitus; blurred vision; nausea; vomiting; muscle twitching; tremors; convulsions; hypotension; bradycardia; arrhythmias; cardiac arrest.
Toxicity
Subcutaneous LD50 in rat is 27 mg/kg. Symptoms of overdose include convulsions, hypoxia, acidosis, bradycardia, arrhythmias and cardiac arrest.
Precaution
Elderly; debilitated patients; child; epilepsy; impaired cardiac conduction or respiratory function; shock; hepatic impairment; myasthenia gravis. Do not to rub or touch the eye while anaesthesia persists. Avoid application for prolonged periods and to extensive areas. Pregnancy, lactation.
Elimination Route
In general, ionized forms (salts) of local anesthetics are not readily absorbed through intact skin. However, both nonionized (bases) and ionized forms of local anesthetics are readily absorbed through traumatized or abraded skin into the systemic circulation.
Pregnancy & Breastfeeding use
Pregnancy Category A. A number of epidemiological studies suggest that there could possibly be an increased risk of oral clefts among newborns of women who were treated with systemic glucocorticosteroids during the first trimester of pregnancy. As a general rule, topical preparations containing corticoids should not be applied during the first trimester of pregnancy.
Lactation: The excretion of effective amounts of glucocorticoid with the breast milk is improbable.
Contraindication
Complete heart block; pyogenic infection at or near the skin. Application to inflamed or infected tissues or to damaged skin mucosa; instillation into the middle ear.
Storage Condition
Store below 25°C.
Innovators Monograph
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