Faktu Pommade

Faktu Pommade Uses, Dosage, Side Effects, Food Interaction and all others data.

Faktu Pommade prevents or diminishes nerve impulse conduction near to the site of admin. It also has membrane-stabilising effect owing to decrease of permeability of the nerve cell to sodium ions.

Dibucaine is an amide-type local anesthetic, similar to lidocaine.

Trade Name Faktu Pommade
Generic Cinchocaine
Cinchocaine Other Names Cinchocaine, Cinchocainum, Cincocainio, Dibucaine
Type
Formula C20H29N3O2
Weight Average: 343.4632
Monoisotopic: 343.225977187
Groups Approved, Vet approved
Therapeutic Class Local & Surface anesthesia
Manufacturer
Available Country Switzerland
Last Updated: September 19, 2023 at 7:00 am
Faktu Pommade
Faktu Pommade

Uses

Faktu Pommade is used for Surface anaesthesia, Haemorrhoids

Faktu Pommade is also used to associated treatment for these conditions: Hemorrhoids, Pruritis of the skin, Pruritus Ani, Skin Irritation

How Faktu Pommade works

Local anesthetics block both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions through sodium channel inhibition. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.

Dosage

Faktu Pommade dosage

Surface anesthesia: Use up to 1% cream or ointment topically for adult or as directed by physician.

Side Effects

Restlessness; excitement; nervousness; paraesthesias; dizziness; tinnitus; blurred vision; nausea; vomiting; muscle twitching; tremors; convulsions; hypotension; bradycardia; arrhythmias; cardiac arrest.

Toxicity

Subcutaneous LD50 in rat is 27 mg/kg. Symptoms of overdose include convulsions, hypoxia, acidosis, bradycardia, arrhythmias and cardiac arrest.

Precaution

Elderly; debilitated patients; child; epilepsy; impaired cardiac conduction or respiratory function; shock; hepatic impairment; myasthenia gravis. Do not to rub or touch the eye while anaesthesia persists. Avoid application for prolonged periods and to extensive areas. Pregnancy, lactation.

Food Interaction

No interactions found.

Elimination Route

In general, ionized forms (salts) of local anesthetics are not readily absorbed through intact skin. However, both nonionized (bases) and ionized forms of local anesthetics are readily absorbed through traumatized or abraded skin into the systemic circulation.

Pregnancy & Breastfeeding use

Pregnancy Category A. A number of epidemiological studies suggest that there could possibly be an increased risk of oral clefts among newborns of women who were treated with systemic glucocorticosteroids during the first trimester of pregnancy. As a general rule, topical preparations containing corticoids should not be applied during the first trimester of pregnancy.

Lactation: The excretion of effective amounts of glucocorticoid with the breast milk is improbable.

Contraindication

Complete heart block; pyogenic infection at or near the skin. Application to inflamed or infected tissues or to damaged skin mucosa; instillation into the middle ear.

Storage Condition

Store below 25°C.

Innovators Monograph

You find simplified version here Faktu Pommade

Faktu Pommade contains Cinchocaine see full prescribing information from innovator Faktu Pommade Monograph, Faktu Pommade MSDS, Faktu Pommade FDA label

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0000002
http://classyfire.wishartlab.com/tax_nodes/C0001253
http://classyfire.wishartlab.com/tax_nodes/C0000056
http://classyfire.wishartlab.com/tax_nodes/C0000056
http://classyfire.wishartlab.com/tax_nodes/C0000128
http://classyfire.wishartlab.com/tax_nodes/C0000089
http://classyfire.wishartlab.com/tax_nodes/C0002448
http://classyfire.wishartlab.com/tax_nodes/C0004144
http://classyfire.wishartlab.com/tax_nodes/C0002239
http://classyfire.wishartlab.com/tax_nodes/C0003633
http://classyfire.wishartlab.com/tax_nodes/C0002484
http://classyfire.wishartlab.com/tax_nodes/C0004139
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0004150
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:247956
http://www.hmdb.ca/metabolites/HMDB0014668
http://www.genome.jp/dbget-bin/www_bget?drug:D00733
http://www.genome.jp/dbget-bin/www_bget?cpd:C07879
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3025
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46506734
https://www.chemspider.com/Chemical-Structure.2917.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48532
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=3339
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=247956
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL1086
https://zinc.docking.org/substances/ZINC000001530939
http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000507
http://www.pharmgkb.org/drug/PA449286
https://www.drugs.com/cdi/dibucaine-ointment.html
https://en.wikipedia.org/wiki/Cinchocaine
*** Taking medicines without doctor's advice can cause long-term problems.
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