Fimagen

Fimagen Uses, Dosage, Side Effects, Food Interaction and all others data.

Fimagen is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimagen was initially approved September 9th, 2010 in South Korea and is marketed under the brand name Kanarb by Boryung Pharmaceuticals.

Fimagen is a selective angiotensin receptor 1 (AR1) inhibitor . It acts to lower blood pressure by inhibiting vasoconstriction

Fimagen
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
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Trade Name	Fimagen
Generic	Fimasartan
Fimasartan Other Names	Fimasartan
Weight	60mg, 120mg
Type	Tablet
Formula	C₂₇H₃₁N₇OS
Weight	Average: 501.65 Monoisotopic: 501.23107982
Groups	Investigational
Therapeutic Class
Manufacturer	Ajanta Pharma Ltd
Available Country	India
Last Updated:	September 19, 2023 at 7:00 am

Uses

Fimagen is an angiotensin II receptor antagonist (ARB) used to treat hypertension and heart failure.

Used for the treatment of hypertension and heart failure .

Fimagen is also used to associated treatment for these conditions: Hypertension,Essential

How Fimagen works

Angiotensin II activates AR1 leading to vasoconstriction and increased noradrenaline release which further increases vasoconstriction via action at α1-adrenergic receptors . It also stimulates secretion of aldosterone which acts to increase sodium and water reabsorption in the renal tubules . Fimagen bind to and antagonizes AR1 preventing vasoconstriction and reducing aldosterone secretion to increase natriuresis leading to a reduction in blood volume. Together these effects produce an anti-hypertensive effect.