FizyCal-M Effervescent Tablet

FizyCal-M Effervescent Tablet Uses, Dosage, Side Effects, Food Interaction and all others data.

Each effervescent tablet contains- Calcium Lactate Gluconate 1358 mg Calcium Carbonate BP 1050 mg equivalent to 600 mg of elemental Calcium Vitamin D3 400 IU as Cholecalciferol USP Multimineral

FizyCal-M Effervescent Tablet
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	FizyCal-M Effervescent Tablet
Generic	Calcium Lactate Gluconate + Calcium Carbonate + Vitamin D3 + Multiminerals
Type	Effervescent Tablet
Therapeutic Class	Multi-vitamin & Multi-mineral combined preparations
Manufacturer	Incepta Pharmaceuticals Ltd.
Available Country	Bangladesh
Last Updated:	October 19, 2023 at 6:27 am

Uses

In the treatment and prevention of Calcium and Vitamin-D deficiency In the treatment and prevention of osteoporosis as an adjunct to other specific therapy

FizyCal-M Effervescent Tablet is also used to associated treatment for these conditions: Acid Reflux, Acid indigestion, Bloating, Calcium Deficiency, Calcium Metabolism Disorders, Calcium and Vitamin D Deficiencies, Colic, Dyspepsia, Gastric Ulcer, Gastroesophageal Reflux, Heartburn, Hemorrhoids, Hot Flushes, Hyperacidity, Hyperphosphataemia, Hypovitaminosis D, Low Bone Density, Osteodystrophy, Osteomalacia, Osteoporosis, Postmenopausal Osteoporosis, Postoperative Gas, Proctitis, Vertebral Fractures, Calcium loss, Gastrointestinal ulceration, Dietary supplementationCalcium Deficiency, Hypovitaminosis D, Osteomalacia, Osteoporosis, Calcium supplementation

How FizyCal-M Effervescent Tablet works

Calcium carbonate is a basic inorganic salt that acts by neutralizing hydrochloric acid in gastric secretions. It also inhibits the action of pepsin by increasing the pH and via adsorption. Cytoprotective effects may occur through increases in bicarbonate ion (HCO₃^-) and prostaglandins. Neutralization of hydrochloric acid results in the formation of calcium chloride, carbon dioxide and water. Approximately 90% of calcium chloride is converted to insoluble calcium salts (e.g. calcium carbonate and calcium phosphate).

Dosage

FizyCal-M Effervescent Tablet dosage

Adolescents and adults: 1 tablet once or twice a dayChildren: 1 tablet once a dayDissolve this effervescent tablet in a glass of water and drink immediately. Do not swallow or chew the tablet.

Side Effects

Very rare: Serious Allergic reaction such as swelling of the face, lips, tongues, and throatRare: Hypercalcemia, HypercalciuriaCommon (less serious): Nausea, Vomiting, Diarrhea, Abdominal pain, constipation, flatulence, bloating, itching, redness/ burning of the skin

Precaution

Patients with a history of renal stones urinary calcium excretion should be measured to exclude Hypercalciuria. During long-term administration of this tablet regular blood and urine calcium levels, as well as kidney function, should be monitored regularly. Consultation with a physician should be required while using other Calcium and Vitamin-D preparation, having a previous history of kidney disorders and certain lung diseases e.g., Sarcoidosis/ Besnier-Boeck disease.

Interaction

This can interact with certain medications if taken at the same time. Physician advocacy should be required while using cardiac glycosides, thiazide diuretics, or corticosteroids. In the case of oral bisphosphonates and sodium fluoride, the drug should be taken at least 3 hrs later of administration of these drugs. This should be taken 1 to 2 hrs before or 4 to 6 hrs after taking certain medications e.g. Tetracycline, cholestyramine, or laxatives.

Volume of Distribution

Calcium is rapidly distributed taken up by skeletal tissues following absorption and distribution into extracellular fluids. Bone contains 99% of the body's calcium and the remaining 1% is approximately equally distributed between intracellular and extracellular fluids.

Elimination Route

Maximal absorption occurs at doses of 500 mg or less taken with food. Oral bioavailability depends on intestinal pH, the presence of food and dosage.

Elimination Route

Excreted mainly in the feces. The majority of renally filtered calcium is reabsorbed in the ascending limb of the loop of Henle and the proximal and distal convoluted tubules. Also secreted by sweat glands.

Pregnancy & Breastfeeding use

This effervescent tablet can be used during pregnancy, in case of a calcium and vitamin D deficiency. However, for supplementation starting during the third trimester of pregnancy, the daily intake should not exceed 1500 mg calcium and 1000 IU vitamin D. This effervescent tablets can be used during breastfeeding.

Contraindication

Hypersensitivity to the Calcium Carbonate or any inactive ingredient of the medication. Hypercalcemia (e.g. in hyperparathyroidism, overdosage of vitamin D, demineralizing tumours such as plasmacytomas and bone metastases), severe hypercalcuria, several renal insufficiency.

Special Warning

USE IN CHILDREN: Calcium carbonate has been extensively studied in children and infants with chronic renal failure and is both safe and effective.

USE IN ELDERLY: In case of elderly patients with renal failure when calcium carbonate is taken constipation may be troublesome one for this group. For this reason, monitoring of serum calcium and phosphate is of course indicated for elderly patients.

Acute Overdose

Symptoms of overdose may include nausea and vomiting, extreme thirst, and constipation. The most serious consequence of acute chronic overdose is hypocalcemia due to Vitamin D toxicity.