Flunisolidum
Flunisolidum Uses, Dosage, Side Effects, Food Interaction and all others data.
Flunisolidum (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Flunisolidum is a synthetic corticosteroid. It is administered either as an oral metered-dose inhaler for the treatment of asthma or as a nasal spray for treating allergic rhinitis. Corticosteroids are naturally occurring hormones that prevent or suppress inflammation and immune responses. When given as an intranasal spray, flunisolide reduces watery nasal discharge (rhinorrhea), nasal congestion, postnasal drip, sneezing, and itching oat the back of the throat that are common allergic symptoms.
Trade Name | Flunisolidum |
Availability | Discontinued |
Generic | Flunisolide |
Flunisolide Other Names | Flunisolida, Flunisolide, Flunisolidum |
Related Drugs | Trelegy Ellipta, prednisone, Breo Ellipta, Xopenex, Dulera, Atrovent, Fasenra |
Type | |
Formula | C24H31FO6 |
Weight | Average: 434.4977 Monoisotopic: 434.210466929 |
Protein binding | Approximately 40% after oral inhalation |
Groups | Approved, Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Flunisolidum is an inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
For the maintenance treatment of asthma as a prophylactic therapy.
Flunisolidum is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Asthma
How Flunisolidum works
Flunisolidum is a glucocorticoid receptor agonist. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. Flunisolidum binds to plasma transcortin, and it becomes active when it is not bound to transcortin.
Food Interaction
No interactions found.Flunisolidum Drug Interaction
Minor: fluticasone / salmeterol, fluticasone / salmeterol, budesonide / formoterol, budesonide / formoterolUnknown: aspirin, aspirin, calcium / vitamin d, calcium / vitamin d, omega-3 polyunsaturated fatty acids, omega-3 polyunsaturated fatty acids, montelukast, montelukast, tiotropium, tiotropium, cyanocobalamin, cyanocobalamin, ascorbic acid, ascorbic acid, cholecalciferol, cholecalciferol
Flunisolidum Disease Interaction
Moderate: hyperadrenocorticism, infections, ocular herpes simplex, ocular toxicities, osteoporosis
Elimination Route
Absorbed rapidly
Half Life
1.8 hours
Innovators Monograph
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