Fluormetholone + Neomycin Sulphate Uses, Dosage, Side Effects and more
Fluorometholone suppresses the migration of polymorphonuclear leukocytes and reversal of increased capillary permeability thus decreasing inflammation.
Neomycin is an aminoglycoside antibiotic. It binds to 30S ribosomal subunits of bacterial ribosome thus inhibiting protein synthesis and generating errors in genetic code transcription causing cell death. It acts against many gram-negative aerobes and some gram-positive aerobes. It lacks activity against fungi, viruses and most anaerobic bacteria.
| Trade Name | Fluormetholone + Neomycin Sulphate |
| Generic | Fluormetholone + Neomycin Sulphate |
| Type | |
| Therapeutic Class | Ophthalmic steroid - antibiotic combined preparations |
| Manufacturer | |
| Available Country | Bangladesh |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Allergic and inflammatory conditions of the eye, Eye allergy, Ocular inflammation
Dosage
Adult: Instil 1 -2 drops 2-4 times/day. May increase dose to 4 hourly in severe cases during the initial 24-48 hr.
Side Effects
Elevated intraocular pressure, optic nerve damage, postsubcapsular cataract formation, delayed wound healing, uveitis, perforation of the globe, keratitis, conjunctivitis, corneal ulcers, loss of accommodation, secondary ocular infections, rarely systemic hypercorticoidism.
See simplified version Fluormetholone + Neomycin Sulphate also Fluormetholone + Neomycin Sulphate in banglaPrecaution
Glaucoma (check intraocular pressure periodically), history of herpes simplex fungal or bacterial infections. Not to be used in mustard gas keratitis and Sjogren's keratoconjunctivitis. May cause corneal and scleral thinning which may lead to perforation in serious cases. Use of steroids after cataract surgery may prolong healing time and increase bleb formation. Pregnancy, lactation; children <2 yr.
Pregnancy & Breastfeeding use
Pregnancy Category-C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Contraindication
Viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), Vaccinia and Varicella, mycobacterial eye infection, ocular fungal infections, untreated eye infections; hypersensitivity.
