Fluormetholone + Neomycin Sulphate

Fluormetholone + Neomycin Sulphate Uses, Dosage, Side Effects, Food Interaction and all others data.

Fluorometholone suppresses the migration of polymorphonuclear leukocytes and reversal of increased capillary permeability thus decreasing inflammation.

Neomycin is an aminoglycoside antibiotic. It binds to 30S ribosomal subunits of bacterial ribosome thus inhibiting protein synthesis and generating errors in genetic code transcription causing cell death. It acts against many gram-negative aerobes and some gram-positive aerobes. It lacks activity against fungi, viruses and most anaerobic bacteria.

Fluormetholone + Neomycin Sulphate
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Fluormetholone + Neomycin Sulphate
Generic	Fluormetholone + Neomycin Sulphate
Type
Therapeutic Class	Ophthalmic steroid - antibiotic combined preparations
Manufacturer
Available Country	Bangladesh
Last Updated:	September 24, 2024 at 5:38 am

Uses

Allergic and inflammatory conditions of the eye, Eye allergy, Ocular inflammation

Dosage

Fluormetholone + Neomycin Sulphate dosage

Adult: Instil 1 -2 drops 2-4 times/day. May increase dose to 4 hourly in severe cases during the initial 24-48 hr.

Side Effects

Elevated intraocular pressure, optic nerve damage, postsubcapsular cataract formation, delayed wound healing, uveitis, perforation of the globe, keratitis, conjunctivitis, corneal ulcers, loss of accommodation, secondary ocular infections, rarely systemic hypercorticoidism.

Precaution

Glaucoma (check intraocular pressure periodically), history of herpes simplex fungal or bacterial infections. Not to be used in mustard gas keratitis and Sjogren's keratoconjunctivitis. May cause corneal and scleral thinning which may lead to perforation in serious cases. Use of steroids after cataract surgery may prolong healing time and increase bleb formation. Pregnancy, lactation; children <2 yr.

Pregnancy & Breastfeeding use

Pregnancy Category-C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Contraindication

Viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), Vaccinia and Varicella, mycobacterial eye infection, ocular fungal infections, untreated eye infections; hypersensitivity.