Fluphenazine Panpharma 25 mg/ml IM/SC Injection

Fluphenazine Panpharma 25 mg/ml IM/SC Injection Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name Fluphenazine Panpharma 25 mg/ml IM/SC Injection
Generic Fluphenazine Decanoate
Weight 25 mg/ml
Type IM/SC Injection
Therapeutic Class Phenothiazine drugs
Manufacturer City Overseas Ltd.
Available Country Bangladesh
Last Updated: September 24, 2024 at 5:38 am
Fluphenazine Panpharma 25 mg/ml IM/SC Injection
Fluphenazine Panpharma 25 mg/ml IM/SC Injection

Uses

In the long-term management of psychotic disorders including: Schizophrenia Mania and Organic brain syndrome.

Dosage

Fluphenazine Panpharma 25 mg/ml IM/SC Injection dosage

Fluphenazine Panpharma 25 mg/ml IM/SC Injection by deep intramuscular injection into the gluteal muscle, test dose 12.5 mg (6.25 mg in elderly), then after 4-7 days 12.5-100 mg repeated at intervals of 14-35 days, adjusted according to response; it is not recommended for children.

Side Effects

The side effects include tardive dyskinesia, sedation, mental confusion; hypotension; hyperprolactinaemia leading to galactorrhoea and amenorrhoea in women; loss of libido, impotence and sterility in males. Also include allergic reactions, cholestatic jaundice, corneal and lens deposists, skin pigmentation. Other potential adverse reactions are agranulocytosis; neuroleptic syndrome.

Precaution

Special precaution should be practiced in presence of convulsive disorders; hepatic, renal, cerebrovascular, respiratory and cardiovascular diseases. Also precaution should be observed in case of phenochromocytoma; bone marrow suppression; elderly or debilitated patients.

Interaction

Fluphenazine reverses antihypertensive effects of Guanethidine, Methyldopa and Clonidine. It also causes lithium toxicity by interacting with it. Antacids may reduce bioavailability of phenothiazines. Additive CNS depressant effects produced with alcohol, barbiturates, hypnotics, sedatives, opiates and antihistamines.

Pregnancy & Breastfeeding use

The safety for the use of Fluphenazine decanoate during pregnancy has not yet been established; therefore the possible hazards should be weighed against the potential benefits when administering this drug to pregnant patients.

Contraindication

Fluphenazine Panpharma 25 mg/ml IM/SC Injection oily Injection is contraindicated in patients with hypersensitivity to the drug. Also contraindicated in comatose or severely depressed states, blood dyscrasias, liver disease, pregnancy (3rd trimester), lactation.

Storage Condition

Store at 15-30°C.

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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