GA-GCB

GA-GCB Uses, Dosage, Side Effects, Food Interaction and all others data.

GA-GCB is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, GA-GCB has also been investigated for use in Type 3 Gaucher disease.

Trade Name GA-GCB
Generic Velaglucerase alfa
Velaglucerase alfa Other Names GA-GCB, Velaglucerasa alfa, Velaglucerase alfa
Type
Formula C2532H3850N672O711S16
Weight 63000.0 Da (approximate)
Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
GA-GCB
GA-GCB

Uses

GA-GCB is an enzyme replacement therapy used for the long-term treatment of for pediatric and adult patients with type 1 Gaucher disease.

GA-GCB is a hydrolytic lysosomal glucocerebroside-specific enzyme indicated for long-term enzyme replacement therapy for pediatric and adult patients with type 1 Gaucher disease.

GA-GCB is also used to associated treatment for these conditions: Gaucher Disease, Type 1

How GA-GCB works

GA-GCB catalyzes the hydrolysis of glucocerebroside, reducing the amount of accumulated glucocerebroside.

Food Interaction

No interactions found.

Volume of Distribution

The mean volume of distribution at steady state ranges from 82 to 108 mL/kg (8.2% to 10.8% of body weight).

Half Life

11-12 minutes.

Clearance

Mean clearance ranges from 6.72 to 7.56 mL/min/kg.

Innovators Monograph

You find simplified version here GA-GCB

*** Taking medicines without doctor's advice can cause long-term problems.
Share