Gadral

Gadral Uses, Dosage, Side Effects, Food Interaction and all others data.

Gadral is a hydroxymagnesium aluminate complex that is converted rapidly in gastric acid to Mg(OH)2 and Al(OH)3, which are absorbed poorly and thus provide a sustained antacid effect

Gadral
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Gadral
Availability	Discontinued
Generic	Magaldrate
Magaldrate Other Names	Aluminium magnesium hydroxide sulfate hydrate, Aluminum magnesium hydroxide sulfate hydrate, Aluminum magnesium hydroxide sulphate hydrate, Hydrate magnesium aluminate activated sulfate, Magaldrate, Magaldrato, Magaldratum, Magnesium aluminate hydrate, Monalium hydrate
Related Drugs	omeprazole, famotidine, Pepcid, Prilosec, ranitidine, calcium carbonate
Type
Formula	Al₅H₃₃Mg₁₀O₄₀S₂
Weight	Average: 1115.3 Monoisotopic: 1111.7570627
Groups	Approved, Withdrawn
Therapeutic Class	Antacids, Anti-dyspeptic/Carminatives
Manufacturer
Available Country	Italy
Last Updated:	September 19, 2023 at 7:00 am

Uses

Gadral is used to relieve symptoms of dyspepsia, heartburn, acid indigestion, sour stomach, gastroesophageal reflux, hiatal hernia and flatulence. It is also prescribed in hyperacidity associated with peptic ulcers, gastritis and esophagitis. Gadral may be given to children if necessary.

Gadral is also used to associated treatment for these conditions: Acid indigestion, Aspiration, Bloating, Calcinosis, Dyspepsia, Gastroesophageal Reflux, Gastrointestinal Bleeding, Heartburn, Hyperacidity, Hyperparathyroidism, Kidney Stones, Peptic Ulcer, Stress Ulcers

Dosage

Gadral dosage

Tablet: 1-3 tablets, after meals and at bed time or as directed by the physician.

Syrup: 2 to 3 teaspoonful, 3 or 4 times daily, half to one hour after or before meal and at bedtime

Side Effects

Constipation and diarrhea may occur.

Food Interaction

Avoid alcohol.

Gadral Drug Interaction

Moderate: rosuvastatinUnknown: amoxicillin / clavulanate, glucose, hydrochlorothiazide, pilocarpine ophthalmic, escitalopram, amlodipine, acetaminophen, tiotropium, diltiazem

Gadral Disease Interaction

Major: constipation, renal dysfunctionModerate: diarrhea

Elimination Route

Aluminium oxide: absorbed Al ions are eliminated in the urine (0.1-0.5 mg of Al in aluminium-containing antacid is absorbed from standard daily doses of antacid) while insoluble or poorly absorbed Al salts in the intestines are excreted through the feces.

Magnesium oxide: absorbed Mg ions (up to 30%) are eliminated in the urine, unabsorbed is excreted in the feces.

Pregnancy & Breastfeeding use

Pregnant women: Gadral may be used in pregnancy if indicated however one should avoid excessive dosage.

Lactating mother: Gadral may pass into breast milk but has not been reported to cause problem in nursing babies.

Contraindication

Gadral is contraindicated in patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal function