Gastrom
Gastrom Uses, Dosage, Side Effects, Food Interaction and all others data.
Gastrom is a prescription eye drop for the treatment of dry eye syndrome. Gastrom represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss from tear evaporation. Gastrom is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis.
| Trade Name | Gastrom |
| Generic | Ecabet |
| Ecabet Other Names | Ecabet, Ecabetum |
| Type | |
| Formula | C20H28O5S |
| Weight | Average: 380.498 Monoisotopic: 380.165744696 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of reflux oesophagitis and peptic ulcer disease.
How Gastrom works
Gastrom reduces the survival of H. pylori in the stomach and inhibits pepsin activity in the gastric juice of experimental animals. Here we have investigated the effects of ecabet on some of the factors involved in the dynamics of the mucosal barrier, i.e. pepsins and mucins. Pepsin, acid and Helicobacter pylori are major factors in the pathophysiology of peptic ulcer disease and reflux oesophagitis. Gastrom also acts as an inhibitor of H. pylori NADPH oxidase as well as urease. Inhibition of these enzymes prevents bacterial adhesion to gastric mucosa.
Innovators Monograph
You find simplified version here Gastrom
