Gianco
Gianco Uses, Dosage, Side Effects, Food Interaction and all others data.
Gianco is a centrally acting muscle relaxant that acts at the reticular formation in the brain stem by blocking voltage-gated sodium and calcium channels
| Trade Name | Gianco |
| Generic | Tolperisone |
| Tolperisone Other Names | Tolperisone |
| Type | |
| Formula | C16H23NO |
| Weight | Average: 245.366 Monoisotopic: 245.177964365 |
| Groups | Investigational |
| Therapeutic Class | Central Depolarizing muscle relaxants, Centrally acting Skeletal Muscle Relaxants |
| Manufacturer | |
| Available Country | Vietnam |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Treatment of painful musculoskeletal disorders with hypermyotonia and decreased motility, especially those resulting from spinal cord injuries, osteoporosis, arthritis, and spasticity. It has also been effective in lumboischial pain, neurolathyrism, knee arthritis, peripheral circulatory diseases, climacteric muscular and vascular complaints, trismus, myogenous headaches, rheumatic diseases accompanied by muscular hypertonia, spasms, pain, inflammatory symptoms and limited motion, and in the post-surgical treatment of traumatologic patients.
Gianco Hydrochloride is a centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation and reduces pain
Gianco is also used to associated treatment for these conditions: Spasticity
Dosage
Gianco dosage
Adult: 150-450 mg daily, administered in 2 or 3 divided doses. The maximum dosage is 450 mg/day.
Children:
- 3 months to 6 years: 1-2 mg/kg/day in 3 divided doses.
- 6 years to 14 years: 2-4 mg/kg/day in 3 divided doses
Side Effects
Diarrhea, dizziness, drowsiness, dryness of the mouth, fall of blood pressure, fatigue, gastric complaints, headaches, hypersensitivity, itching, muscle pain, muscle weakness, rash, and somnolence.
Precaution
In case of children, the prescribed dose and duration of treatment should closely be observed.
Interaction
Concomitant use of Methocarbamol with Gianco Hydrochloride has been reported to cause disturbance of visual accommodation.
Pregnancy & Breastfeeding use
Gianco Hydrochloride should be used in pregnancy according to physician's advice. Gianco hydrochloride should not be used during breast-feeding.
Contraindication
Hypersensitivity, Myasthenia Gravis and nursing mother.
Acute Overdose
Excitability has been noted after ingestion of high doses by children. In suicide studies of three isolated cases, it is believed that ingestion of tolperisone was the cause of death.
Storage Condition
Gianco Hydrochloride should be stored below 30° C. Keep out of reach of children
Innovators Monograph
You find simplified version here Gianco
Gianco contains Tolperisone see full prescribing information from innovator Gianco Monograph, Gianco MSDS, Gianco FDA label
FAQ
What is Gianco used for?
Gianco is a muscle relaxant used to relieve spasticity after stroke in adults.Gianco is an oral, centrally acting muscle relaxant.
How safe is Gianco?
Gianco hydrochloride represents an effective and safe treatment of central post stroke spasticity, neurolathyrism, and painful reflex muscle spasm without the typical side effects of centrally active muscle relaxants.
What are the common side effects of Gianco?
The common side effects of Gianco are include: tiredness, dizziness, nausea, mouth dryness, increase in liver enzymes. Contraindications: myasthenia gravis, pregnancy, breast feeding.
Is Gianco safe during pregnancy?
Gianco should be avoided, particularly during the first trimester of pregnancy to avoid embryo toxicity.
Is Gianco safe during breastfeeding?
This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not clinically established.
Can I drink alcohol with Gianco?
Gianco is not sedating and does not interact with alcohol.
How long does Gianco take to work?
Gianco is absorbed nearly completely from the gut and reaches its peak blood plasma concentration after 1.5 hours.
Is Gianco a sedative?
Gianco does not cause any sedation and does not impair reaction times.
How do you take Gianco?
Take Gianco with food.Take it with or after food or a glass of milk. Do not take in larger amounts than advised/prescribed.
Does Gianco cause drowsiness?
The most common adverse effects were asthenia and sleepiness(drowsiness).
When should not I take Gianco?
This medicine is not recommended for use in patients with a known allergy to Gianco or any other inactive ingredient present along with it.
What happens if I miss a dose?
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose.
What happens if I overdose?
Seek emergency medical treatment or contact the doctor in case of an overdose.
