Gpp(NH)p Uses, Dosage, Side Effects and more

A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of adenylate cyclase.

Trade Name Gpp(NH)p
Generic Phosphoaminophosphonic acid guanylate ester
Phosphoaminophosphonic acid guanylate ester Other Names 5'-guanylylimidodiphosphate, GMP-PNP, Gpp(NH)p, Guanosine 5'-[beta,gamma-imido]triphosphate, Guanylyl imidodiphosphate
Type
Formula C10H17N6O13P3
Weight Average: 522.1957
Monoisotopic: 522.006644196
Groups Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated: January 7, 2025 at 1:49 am

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