Gpp(NH)p Uses, Dosage, Side Effects and more
A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of adenylate cyclase.
| Trade Name | Gpp(NH)p |
| Generic | Phosphoaminophosphonic acid guanylate ester |
| Phosphoaminophosphonic acid guanylate ester Other Names | 5'-guanylylimidodiphosphate, GMP-PNP, Gpp(NH)p, Guanosine 5'-[beta,gamma-imido]triphosphate, Guanylyl imidodiphosphate |
| Type | |
| Formula | C10H17N6O13P3 |
| Weight | Average: 522.1957 Monoisotopic: 522.006644196 |
| Groups | Experimental |
| Therapeutic Class | |
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| Last Updated: | January 7, 2025 at 1:49 am |
