GS-441524

GS-441524 Uses, Dosage, Side Effects, Food Interaction and all others data.

GS-441524 is an adenosine nucleotide analog antiviral, similar to remdesivir. This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent. GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis Virus, a coronavirus that only infects cats.

Table Of contents

• GS-441524
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	GS-441524
Generic	GS-441524
Type
Formula	C12H13N5O4
Weight	Average: 291.267 Monoisotopic: 291.096753919
Groups	Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

GS-441524 is an experimental nucleoside analog antiviral investigated for its use in the treatment of Ebola and SARS-CoV-2 infections.

How GS-441524 works

GS-441524 is phosphorylated 3 times to form the active nucleoside triphosphate, which is incorporated into the genome of virions, terminating its replication.

Elimination Route

GS-441524 has been found to transport poorly into cells compared to remdesivir.

Innovators Monograph

You find simplified version here GS-441524