Hantina
Hantina Uses, Dosage, Side Effects, Food Interaction and all others data.
A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial wounds, burns, ulcers, and skin infections. Nitrofurazone has also been administered orally in the treatment of trypanosomiasis.
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Trade Name | Hantina |
Generic | Nitrofural |
Nitrofural Other Names | Furacilin, Nitrofural |
Type | |
Formula | C6H6N4O4 |
Weight | Average: 198.1362 Monoisotopic: 198.0389047 |
Groups | Approved, Investigational, Vet approved |
Therapeutic Class | |
Manufacturer | |
Available Country | Brazil |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Hantina is a topical antibacterial for the prevention and treatment of bacterial infections of the skin.
For the treatment of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Hantina is also used to associated treatment for these conditions: Skin Infections
How Hantina works
The exact mechanism of action is unknown. Nitrofurazone inhibits several bacterial enzymes, especially those involved in the aerobic and anaerobic degradation of glucose and pyruvate. This activity is believed also to affect pyruvate dehydrogenase, citrate synthetase, malate dehydrogenase, glutathione reductase, and pyruvate decarboxylase.
Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Elimination Route
Well absorbed.
Half Life
5 hours
Innovators Monograph
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