Hong Kang Wei Si

Hong Kang Wei Si Uses, Dosage, Side Effects, Food Interaction and all others data.

Hong Kang Wei Si is a non-opioid analgesic and though it acts centrally, its mechanism is not defined. It also exerts antimuscarinic and sympathomimetic actions.

Hong Kang Wei Si
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Hong Kang Wei Si
Generic	Nefopam
Nefopam Other Names	Nefopam
Type
Formula	C₁₇H₁₉NO
Weight	Average: 253.345 Monoisotopic: 253.146664236
Groups	Approved, Investigational
Therapeutic Class	Non opioid analgesics, Non-Opioid Analgesics
Manufacturer
Available Country	China
Last Updated:	September 19, 2023 at 7:00 am

Uses

Hong Kang Wei Si Hydrochloride is used for the relief of acute pain, including post-operative, dental, musculo-skeletal and acute traumatic pain. It is also used for chronic pain like cancer pain.

Hong Kang Wei Si is also used to associated treatment for these conditions: Pain

Dosage

Hong Kang Wei Si dosage

Tablet-

Adults: Dosage may range from 30 to 90 mg three times daily depending on response. The recommended starting dosage is 2 tablets three times daily.
Elderly: Elderly patients may require reduced dosage due to slower metabolism. It is strongly recommended that the starting dose does not exceed 1 tablet 3 times daily.

Injection-

Adult: 20 mg by IM injection, repeated every 6 hours if necessary. It also be given by slow IV injection in similar dose.
Children: Not recommended for children under the age of 12 years.

Side Effects

Hong Kang Wei Si Hydrochloride is generally well tolerated. However the most common side-effects are nausea, nervousness, dry mouth, lightheadedness and urinary retention.The less common side-effects are vomiting, blurred vision, drowsiness, sweating, insomnia, headache, confusion, hallucinations, tachycardia and aggravation of angina.

Precaution

Hong Kang Wei Si Hydrochloride should be used with caution in patients with glaucoma and with or at risk of urinary retention. Caution should be exercised when Hong Kang Wei Si is administered concurrently with tricyclic antidepressants. Caution should also be exercised in patients with a history of ischaemic heart disease.

Pregnancy & Breastfeeding use

Pregnancy: Hong Kang Wei Si Hydrochloride is not recommended for pregnant women.

Lactation: Evidence suggests that nefopam is excreted in human milk. A decision should made whether to discontinue nursing or discontinue the medication, taking into account the potential for adverse effects for the foetus and the importance of treatment to the mother.

Contraindication

Hong Kang Wei Si Hydrochloride is contraindicated in patients with a history of convulsive disorders and should not be given to patients taking monoamine oxidase (MAO) inhibitors. It is also should not be used in the treatment of myocardial infarction.

Acute Overdose

Hong Kang Wei Si toxicity is manifested by neurological symptoms (convulsions, hallucinations, agitation) and cardiovascular response (tachycardia with hyperdynamic circulation). Supportive treatment is suggested including gastric lavage, forced emesis and diuresis. Oral administration of activated charcoal may help prevent absorption. Convulsions and hallucinations may be controlled with diazepam. Beta-adrenergic blockers may be of use in controlling the cardiovascular complications.