Hydra Seal Spf
Hydra Seal Spf Uses, Dosage, Side Effects, Food Interaction and all others data.
Avobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as wide spectrum sunscreens. Avobenzone is very sensitive to light, to increase its stability and duration of action, photostablizers are added in the sunscreen product. Avobenzone has an absorption maximum of 357 nm. Sunscreens containing avobenzone is indicated for providing protection from the sun. In addition to limiting the skin's exposure to the sun, using sunscreen agents may help reduce long-term sun damage such as premature aging of the skin and skin cancer.
Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage and increased risk of skin cancer.
It is a common ingredient in many commercially available sunscreens. There are no reported adverse effects from homosalate.
Acts as UV filters.
Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and decrease the risk of percutaneous absorption. Its use in pharmaceutical and cosmetic formulations is approved by FDA.
Acts as a photoprotective agent that protects the skin by preventing and minimizing the damaging effects of ultraviolet (UV) rays of natural light. The cellular effects of UV irradiation include DNA damage, cell cycle arrest, immunological depression, apoptosis, and transcriptional changes .
Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other UV filters. Octyl salicylate appears to have a good safety profile. It covers wavelength in the range 295-315 nm, peak at 307-310 nm.
It is an ester of salicylic acid and 2-ethylhexanol. The salicylate portion of the molecule absorbs ultraviolet light to protect skin from the harmful effects of exposure to sunlight, while the ethylhexanol portion functions as an emollient.
Data not found.
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone.
Trade Name | Hydra Seal Spf |
Generic | Octinoxate + Oxybenzone + Avobenzone + Octisalate + Homosalate |
Weight | 7.5% |
Type | Lotion |
Therapeutic Class | |
Manufacturer | Glenmark Pharmaceuticals |
Available Country | India |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Avobenzone is a sunscreen agent found in sunscreens that absorbs UV rays.
Sun protection factor, added in the sunscreen products for its wide spectrum ultraviolet absorption properties.
As ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer.
Octinoxate is a sunscreen agent found in sunscreens that absorbs UV rays.
As an active ingredient in sunscreens and lip balms. Used for protection against damaging effects of sun rays.
Ingredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer.
Oxybenzone is a sunscreen agent found in sunscreens that absorbs UV rays.
Used as an ingredient in sunscreen and other cosmetics.
Hydra Seal Spf is also used to associated treatment for these conditions: SunburnSunburnSunburnSunburnSunburn
How Hydra Seal Spf works
It blocks UVA I, UVA II, and UVB wavelengths, thereby limiting the impact of UV rays on skin. Diminish the penetration of ultraviolet (UV) light through the epidermis by absorbing UV radiation within a specific wavelength range. The amount and wavelength of UV radiation absorbed are affected by the molecular structure of the sunscreen agent.
Homosalate has the ability to convert incident ultraviolet radiation into less damaging infrared radiation (heat).
Absorbs UV-B (predominantly) and UV-A rays while accumulating in the outermost layer of the epidermis. Like any other photoprotective agents, octinoxate prevents the damage to cells and deoxyribonucleic acid (DNA) by reducing the p53 protein expression following UV exposure and also increases the skin's tolerability to UV rays .
Chemical sunscreen, it acts through absorption of UVB light and not UVA.
Oxybenzone absorbs UV-A ultraviolet rays, preventing them from reaching the skin.
Toxicity
A minimum toxic dose has not been established. Significant toxicity is not expected
LD50: Not available.
Slightly hazardous in case of skin contact, eye contact, ingestion and inhalation. Octinoxate may form reactive singlet oxygen species and induce anti-estrogenic effects . UV-induced molecular breakdown of octinoxate may interfere with cellular processes or induce oxidative damage in human skin . The NOAEL (no observed adverse effect level) is 450 mg/kg bw/day for fertility and reproductive performance, for systemic parental and developmental toxicity in Wistar rats .
LD50, (oral, rat): > 5000 mg/Kg. LD50 (dermal, rabbit): > 5000 mg/Kg.
Volume of Distribution
For local use only, no systemic absorption.
Intended for local use only, no systemic absorption.
Elimination Route
For local use only, no systemic absorption.
Can be systemically absorbed after skin application, being found in the deeper layers of the stratum corneum as well as urine, plasma, and breast milk . The mean maximum plasma concentration detected after application of 2mg/cm2 sunscreen was 7ng/mL in women and 16ng/mL in men .
Intended for local use only, no systemic absorption.
Half Life
For local use only, no systemic absorption.
Intended for local use only, no systemic absorption.
Clearance
For local use only, no systemic absorption.
Intended for local use only, no systemic absorption.
Elimination Route
For local use only, no systemic absorption.
Can be detected in urine in unchanged form .
Intended for local use only, no systemic absorption.
In vivo studies show oxybenzone is abosorbed transdermally (through the skin) and is excreted in the urine.
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