Hydrolate

Hydrolate Uses, Dosage, Side Effects, Food Interaction and all others data.

Hydrolate is an ethylenediamine derivative antihistamine with antimuscarinic and sedative properties.

Hydrolate
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Hydrolate
Generic	Mebhydrolin
Mebhydrolin Other Names	Mebhydrolin
Weight	50mg
Type	Tablet
Formula	C₁₉H₂₀N₂
Weight	Average: 276.383 Monoisotopic: 276.162648652
Groups	Experimental
Therapeutic Class	Sedating Anti-histamine
Manufacturer	Rex Pharmaceuticals Pakistan
Available Country	Pakistan
Last Updated:	September 19, 2023 at 7:00 am

Uses

Allergic disease or symptoms such as urticaria, pruritus of various origin, eczema, itching, drug rash, insect bites, allergic conjunctivitis, dermatitis of nutritional origin, hay fever, vasomotor rhinitis, allergic asthma.

Hydrolate is also used to associated treatment for these conditions: Allergies

Dosage

Hydrolate dosage

Adult: 100-300 mg/day or 2-6 tablets daily.

Child:

2-5 year: 50-150 mg/day or 1-3 tablets daily;
5-10 year: 100-200 mg/day or 2-4 tablets daily;
>10 year: 100-300 mg/day or 2-6 tablets daily.

Treatment should be given in several single doses daily. Hydrolate may be swallowed during or shortly after meals. For children, the tablet may be crushed and mixed with food.

Side Effects

Lassitude, dizziness, hypotension, muscular weakness, nausea, vomiting, diarrhoea or constipation, epigastric pain, headache, blurred vision, tinnitus, depression, nightmares, anorexia, dryness of the mouth, tightness of the chest, tingling, sedation, drowsiness etc. may occur.

Precaution

Closed-angle glaucoma; urinary retention, prostatic hyperplasia or pyloroduodenal obstruction; epilepsy. Elderly. Pregnancy. May impair ability to drive or operate machinery

Interaction

Enhanced sedation with alcohol or other CNS depressants. Additive antimuscarinic effects with MAOIs, atropine, TCAs. May mask warning symptoms caused by ototoxic agents e.g. aminoglycoside antibiotics.

Pregnancy & Breastfeeding use

Safety in pregnancy and lactation has not been established.

Contraindication

Hypersensitivity to any of the ingredients of Hydrolate tablet or to mebhydrolin, prostatic hypertrophy, narrow-angle glaucoma, first trimester of pregnancy