Hydroxyethylcellulose
Hydroxyethylcellulose Uses, Dosage, Side Effects, Food Interaction and all others data.
Hydroxyethylcellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties. It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. It is often used as an ingredient in ophthalmic pharmaceutical preparations such as artificial tear solutions and adjunct agent in topical drug formulations to facilitate the delivery of drugs with hydrophobic character.
Hydroxyethylcellulose acts as a demulcent by relieving inflammation or irritation and dryness of eyes. It acts as one of the key ingredient and viscosity-enhancing agent to prolong corneal contact time and increase intraocular drug levels .
| Trade Name | Hydroxyethylcellulose |
| Generic | Hydroxyethyl cellulose |
| Hydroxyethyl cellulose Other Names | Cellulose hydroxyethyl ether, Cellulose hydroxyethylate, hydroxyethylcellulose |
| Type | |
| Formula | C36H70O19 |
| Weight | Average: 806.937 Monoisotopic: 806.451130034 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Hydroxyethylcellulose is an ingredient used in formulations to alleviate irritation of the skin.
For alleviating surface irritation in topical ocular administrations, such as artificial tear solutions. Hydroxyethylcellulose is also found in topical formulations to aid in more efficient drug diffusion across the membranes.
How Hydroxyethylcellulose works
Interacts with the solid surface through hydrogen bonding to thicken and prolong the formation time of a water-retaining film. Hydroxyethylcellulose acts as a drug carrier or microsphere to entrap other drug molecules and form a viscous gel-like dispersion, enabling drug diffusion across biological membranes .
Toxicity
May cause chemical pneumonitis in case of inhalation and skin irritation. Animal data suggests potential alteration in female fertility.
Food Interaction
No interactions found.Innovators Monograph
You find simplified version here Hydroxyethylcellulose
