Hyoscine Hydrobromide

Hyoscine Hydrobromide Uses, Dosage, Side Effects, Food Interaction and all others data.

Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.

Hyoscine Hydrobromide
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Hyoscine Hydrobromide
Generic	Hyoscine Hydrobromide
Type
Therapeutic Class	Anti-emetic drugs
Manufacturer	Wockhardt UK Ltd
Available Country	United Kingdom
Last Updated:	September 19, 2023 at 7:00 am

Uses

Motion sickness

Dosage

Hyoscine Hydrobromide dosage

Adult & Children over 12 years: 300 mcg 30 mins before journey, then 300 mcg 6 hrly if needed. Max: 3 doses in 24 hr.

Children 4-12 years: 1 tablet (150 mcg) 30 mins before journey. Maximum 2 tablet in 24 hours.

Children 3-4 years: ½ tab 30 mins before journey. Maximum 1 tablet in 24 hours.

Side Effects

Flushing, postural hypotension, tachycardia, fibrillation. Rarely psychotic reactions. Dizziness, drowsiness, fatigue, headache, memory loss. Dry skin, erythema, increased sensitivity to light, rash. Bloatedness, constipation, dry throat, dysphagia, nausea, vomiting, xerostomia. Dysuria, urinary retention. Tremor, weakness. Impaired accommodation, blurred vision, cycloplegia, dryness, narrow-angle glaucoma, increased intraocular pain, itching, photophobia, pupil dilation. Dry nose. Decreased diaphoresis, heat intolerance. Ophthalmic: Somnolence, dermatitis, oedema, exudate, follicular conjunctivitis, increased IOR local irritation, photophobia, vascular and respiratory congestion.

Precaution

Hepatic/renal disease, pyloric stenosis, urinary retention, prostatic hyperplasia, psychosis, seizure disorders, ulcerative colitis, coronary artery disease, tachyarrhythmias, heart failure, hypertension. Elderly, children, pregnancy, lactation

Interaction

Additive sedative effects with alcohol or other CNS depressants. Reduced effects with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine, tacrine).

Pregnancy & Breastfeeding use

Pregnancy Category C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks