Hyoscine-N-Butylbromide GPO

Hyoscine-N-Butylbromide GPO Uses, Dosage, Side Effects, Food Interaction and all others data.

Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.

Trade Name Hyoscine-N-Butylbromide GPO
Generic Hyoscine Butylbromide
Type
Therapeutic Class Anticholinergics (antimuscarinics)/ Anti-spasmodics
Manufacturer
Available Country Thailand
Last Updated: September 19, 2023 at 7:00 am
Hyoscine-N-Butylbromide GPO
Hyoscine-N-Butylbromide GPO

Uses

Hyoscine butylbromide is an antispasmodic medicine which is taken to relieve cramps in the stomach, intestines or bladder. In particular, it helps to ease bloating and the spasm-type pain that can be associated with irritable bowel syndrome and diverticular disease. It works by relaxing some of the muscles in your gastrointestinal and urinary systems.

Hyoscine butylbromide is available on prescription. You can also buy it from a pharmacy, without a prescription, to relieve the symptoms of irritable bowel syndrome, providing your symptoms have previously been diagnosed by a doctor.

There is also a medicine called hyoscine which is taken to prevent travel sickness. There is more information about this in a separate medicine leaflet called Hyoscine for travel sickness.

Dosage

Hyoscine-N-Butylbromide GPO dosage

Tablets: The usual dose of Hyoscine tablets is 10 to 20 mg tablets per day.If you need to take this medication regularly, then the usual dose is 10 mg tablet 3 to 5 times a day. The maximum dose is 6 tablets per day.

Injection: The usual doseof Hyoscine Injection is 10mg to 20mg given byintramuscular (into a muscle), intravenous (into a vein), orsubcutaneous(under the skin) injection. The maximum daily dose is 100mg.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here,do not change the way that you are using the medication without consulting your doctor.

Swallow the tablets whole with a glass of water. Do not crush or chew the tablets.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Side Effects

Hyoscine butylbromide side-effects (these affect less than 1 in 100 people) are Dry mouth, Dry skin, sweating, Itchy skin rash

Precaution

Hepatic/renal disease, pyloric stenosis, urinary retention, prostatic hyperplasia, psychosis, seizure disorders, ulcerative colitis, coronary artery disease, tachyarrhythmias, heart failure, hypertension. Elderly, children, pregnancy, lactation.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Interaction

Additive sedative effects with alcohol or other CNS depressants. Reduced effects with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine, tacrine).

Pregnancy & Breastfeeding use

Pregnancy Category C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Contraindication

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking hyoscine butylbromide it is important that your doctor or pharmacist knows:

  • If you are pregnant or breast-feeding.
  • If you have prostate problems.
  • If you have any other digestive system problems, such as reflux disease, diarrhoea, ulcerative colitis, or severe constipation.
  • If you have high blood pressure, or if you have recently had a heart attack.
  • If you have glaucoma. This is a condition where the pressure in your eyes is raised.
  • If you have been told by a doctor that you have a fast heart rate.
  • If you have Down's syndrome.
  • If you are less than 12 years old or over 65 years old.
  • If you have been told you have nerve damage, a condition called autonomic neuropathy.
  • If you have a condition that causes muscle weakness, called myasthenia gravis.
  • If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
  • If you have ever had an allergic reaction to a medicine.

Storage Condition

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Innovators Monograph

You find simplified version here Hyoscine-N-Butylbromide GPO

FAQ

What is Hyoscine-N-Butylbromide GPO used for?

Hyoscine-N-Butylbromide GPO is an anticholinergic medication used to treat crampy abdominal pain, esophageal spasms, renal colic, and bladder spasms. It is also used to improve respiratory secretions at the end of life.

How safe is Hyoscine-N-Butylbromide GPO?

Hyoscine-N-Butylbromide GPO is barely absorbed and detectable in the blood and does not penetrate the blood-brain barrier, and is, therefore, generally well tolerated. Few adverse events have been reported; in particular, no significant increases in the incidence of anticholinergic-related adverse effects have been observed.

How does Hyoscine-N-Butylbromide GPO work?

Hyoscine-N-Butylbromide GPO reduces spasms by relaxing smooth muscles within the stomach, intestines, bladder and urethra.

What are the common side effects of Hyoscine-N-Butylbromide GPO?

Common side effects of Hyoscine-N-Butylbromide GPO are include: Constipation, dry mouth, trouble urinating, or nausea could occur. If these continue or are bothersome, notify your doctor promptly. Very unlikely but report: rash, itching, swelling of the hands or feet, trouble breathing, increased pulse, dizziness, diarrhea, vision problems, eye pain.

Is Hyoscine-N-Butylbromide GPO safe during pregnancy?

No adverse effects during pregnancy or lactation have been proven; however, its use is recommended with caution under the first trimester.

Is Hyoscine-N-Butylbromide GPO safe during breastfeeding?

No adverse effects during lactation have been proven; however, its use is recommended with caution under the first trimester.

Can I drink alcohol with Hyoscine-N-Butylbromide GPO?

Do not drink alcohol while you are being given this medicine. Alcohol may increase the chance of side effects such as drowsiness.

Can I drive after taking Hyoscine-N-Butylbromide GPO?

Do not drive or ride a bike until you can see clearly again. Do not take your next dose of Hyoscine-N-Butylbromide GPO if your vision is still blurry. Speak to your doctor or pharmacist if your vision has not returned to normal a day after taking your last dose.

When is the best time to take Hyoscine-N-Butylbromide GPO?

Take Hyoscine-N-Butylbromide GPO tablets when you have stomach cramps or period pain. Hyoscine-N-Butylbromide GPO does not usually upset your stomach, so you can take it with or without food.

How often can I take Hyoscine-N-Butylbromide GPO?

It is usual to be prescribed one or two tablets to take three times a day, although your doctor may increase your dose to two tablets four times daily if needed. Swallow the tablets with a drink of water.

How long does Hyoscine-N-Butylbromide GPO take to work?

Hyoscine-N-Butylbromide GPO has a fast onset of action, working in just 15 minutes.

How long can I take Hyoscine-N-Butylbromide GPO?

Do not take Hyoscine-N-Butylbromide GPO for longer than 2 weeks unless your doctor tells you to. Talk to your doctor if your symptoms change, get worse or have not improved after 2 weeks.

What happens if I take too much Hyoscine-N-Butylbromide GPO?

Seek medical advice if you have used more than the recommended or prescribed dose of Hyoscine-N-Butylbromide GPO. Symptoms of an overdose may include: drowsiness, dry mouth, difficulty passing urine, reddening of the skin, decreased gastrointestinal tract movement, fast heart rate and sight disturbances.

Who should not take Hyoscine-N-Butylbromide GPO?

You should not take Hyoscine-N-Butylbromide GPO if you have myasthenia gravis (a condition where the muscles become weak and tire easily) a condition where your bowel is blocked and does not work properly, such as paralytic ileus. are 40 years or over. are pregnant, trying to get pregnant or breastfeeding.

What happen If I missed dose of Hyoscine-N-Butylbromide GPO?

Oral forms/Suppositories: If you missed a dose of Hyoscine-N-Butylbromide GPO, take it as soon as you remember. If it is time for the next dose, skip the missed dose. Take your next dose at your usual time. Do not double the dose.
Injections: Since Hyoscine-N-Butylbromide GPO is given in the hospital setting by a qualified healthcare professional, the likelihood of missing dose is very low. If you miss a scheduled appointment for a dose of this medicine, contact your doctor immediately for further instructions.

Can Hyoscine-N-Butylbromide GPO affects my liver?

Hyoscine-N-Butylbromide GPO should be used with extreme caution in children under 6 years and only under the supervision of a qualified healthcare professional.

Does Hyoscine-N-Butylbromide GPO increase heart rate?

The intravenous injection of Hyoscine-N-Butylbromide GPO. gr. 1/100 will usually cause a rise in pulse rate.

Is Hyoscine-N-Butylbromide GPO good for kidney stones?

Furthermore, it does not facilitate passage of ureteral stones and has no effect on expulsion rate. Hyoscine-N-Butylbromide GPO is often used where urinary tract smooth muscle spasm is thought to be part of the pathophysiological process.

Is Hyoscine-N-Butylbromide GPO good for acid reflux?

It was found that Hyoscine-N-Butylbromide GPO does not induce gastro-oesophageal reflux in the majority of patients, or interfere with detection of a hiatus hernia.


*** Taking medicines without doctor's advice can cause long-term problems.
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