Hypomer Ophthalmic Gel 0.3%+0.22%

Hypomer Ophthalmic Gel 0.3%+0.22% Uses, Dosage, Side Effects, Food Interaction and all others data.

This eye for all patients with ocular discomfort. The slight hypotonicity of the gel is rapidly "neutralised" by the slightly hypertonic tear fluid caused by dry eyes.

Trade Name Hypomer Ophthalmic Gel 0.3%+0.22%
Generic Hypromellose + Carbomer
Weight 0.3%+0.22%
Type Ophthalmic Gel
Therapeutic Class Drugs for Dry eyes
Manufacturer Aristopharma Ltd.
Available Country Bangladesh
Last Updated: October 19, 2023 at 6:27 am
Hypomer Ophthalmic Gel 0.3%+0.22%
Hypomer Ophthalmic Gel 0.3%+0.22%

Uses

This Gel is a substitute tear fluid for the alleviation of dry eye conditions as well as for the management of an unstable tear film.

Hypomer Ophthalmic Gel 0.3%+0.22% is also used to associated treatment for these conditions: Dry Eye Syndrome (DES), Dry Eyes, Red eyeDry Eyes, Ocular Discomfort, Ocular Irritation

How Hypomer Ophthalmic Gel 0.3%+0.22% works

Promotes corneal wetting by the stabilization and thickening the precorneal tear film and prolonging the tear film breakdown time, which is usually shortened in dry eye conditions. Hypromellose also acts to lubricate and protect the eye .

The surface active properties of the vehicles found in artificial tears solutions act to stabilize the tear film and increase tear viscosity to prevent delay tear evaporation and delay tear drainage .

In the intact eye, the corneal surface is moistened primarily by the mucin that is produced in the conjunctiva. Mucin is adsorbed on the corneal surface and forms a hydrophilic surface. This creates a moisture barrier. In the typical dry eye, and particularly in case of mucin deficiency, the application of artificial tear fluid is highly recommended. Both its surface activity and its adsorptive capacity make hypromellose optimal for this use. Hypromellose has a physical-chemical action and leads to, in an aqueous solution, a reduced surface tension as well as an increased level of viscosity. Hypromellose adheres well to the cornea and conjunctiva and provides ample moisture. Irritation symptoms caused by blinking, which occur in the case of tear fluid deficiency, are therefore decreased and symptoms of epithelial desiccation are also alleviated .

Dosage

Hypomer Ophthalmic Gel 0.3%+0.22% dosage

Instill 1 drop in the conjunctival sac of the affected eye(s), as needed. The frequency of administration depends on the severity of the condition. On average, one drop is administered 1-3 times daily. If needed, This Gel may be administered more frequently.

Side Effects

This Gel is very well tolerated by users. However, some cases of burning, stinging, allergic reactions or red eyes after instillation have been reported. Transient blurring of vision after administration has also been reported.

Toxicity

LD 50 (Rat): > 5 g/kg .

Hypromellose is considered low toxicity to non-toxic .

Adverse events may include blurred vision and contact dermatitis . Hypersensitivity and intolerance reactions may occur (for example, eye burning, pain, increased lacrimation, a sensation of foreign body, conjunctival hyperemia, eyelid swelling, pruritus). The stickiness sensation of the eyelids, the decreased sense of smell, photosensitivity .

Precaution

  • If eye pain, changes in vision, continued redness or irritation of the eye are noticed, this Gel must be discontinued and a doctor should be consulted.
  • If this gel colour is change or becomes cloudy, the product should not be used.
  • It should never be injected subconjunctivally, nor should be directly introduced into the anterior chamber of the eye.
  • It is not intended to be used during surgery.

Interaction

Hypromellose can be used in combination with contact lenses. No compatibility study with lens material is available.

Elimination Route

Not systemically absorbed .

Pregnancy & Breastfeeding use

Use in pregnancy & lactation: There is no experience regarding the safety of this Gel in human pregnancy or lactation.

Contraindication

Hypersensitivity to any of the ingredients of this product.

Special Warning

Use in children: Studies in the pediatric population have not been performed.

Use in elderly patients: There is no indication that dosage needs to be modified for the elderly.

Acute Overdose

No case of overdose has been reported.

Storage Condition

Store in a cool dry place, away from light. Keep out of reach of children. Do not touch tip of the tube surface since this may contaminate the gel. After one month of the opening do not use the medicine of tube.

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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