Hyronate 0.2% Intra-articular Injection
Hyronate 0.2% Intra-articular Injection Uses, Dosage, Side Effects, Food Interaction and all others data.
Sodium hyaluronate is a polysaccharide which functions as a tissue lubricant. It is widely used in ophthalmic surgery because it forms a viscoelastic solution in water which makes it a suitable substitute for aqueous and vitreous humour.
| Trade Name | Hyronate 0.2% Intra-articular Injection |
| Generic | Sodium Hyaluronate |
| Weight | 0.2% |
| Type | Intra-articular Injection |
| Therapeutic Class | Drugs for Osteoarthritis |
| Manufacturer | Incepta Pharmaceuticals Ltd. |
| Available Country | Bangladesh |
| Last Updated: | September 24, 2024 at 5:38 am |
Uses
Hyronate 0.2% Intra-articular Injection is used for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy, and to simple analgesics, e.g., acetaminophen.
Hyronate 0.2% Intra-articular Injection is a viscous solution consisting of a high molecular weight fraction of purified natural sodium hyaluronate in buffered physiological sodium phosphate. It has a pH of 5.5-7.0. Hyaluronic acid is an important component of the body's extracellular matrix and is present in a particularly high concentration in cartilage and synovial fluid. Endogenous hyaluronic acid provides viscosity and elasticity to synovial fluid, which is fundamental for its lubricating and shock absorbing properties. It is essential for the correct structure of proteoglycans in articular cartilage. In osteoarthritis there is an insufficient amount of and a chance in the quality of hyaluronic acid in synovial fluid and cartilage. The intra-articular administration of hyaluronic acid into arthritic joints with degenerating cartilage surfaces and pathologically altered synovial fluid improved functions.
Dosage
Hyronate 0.2% Intra-articular Injection dosage
Hyronate 0.2% Intra-articular Injection is administered by intra-articular injection. A treatment cycle consists of five injections given at weekly intervals. Some patients may experience benefit with three injections given at weekly intervals. Inject the full 2 ml in one knee only. If treatment is bilateral, a separate injection should be used for each knee.
Side Effects
The common side-effects include gastrointestinal complaints, injection site pain, knee swelling/effusion, local skin reactions (rash, ecchymosis), pruritus, and headache.
Precaution
Use caution when injecting Hyronate 0.2% Intra-articular Injection into patients who are allergic to avian proteins, feathers, and egg products. Strict aseptic administration technique must be followed. Remove joint effusion, if present, before injecting Hyronate 0.2% Intra-articular Injection. Do not use the same syringe for removing joint effusion and for injecting Hyronate 0.2% Intra-articular Injection. It is recommended that the patient avoid any strenuous activities or prolonged (i.e., more than 1 hour) weight-bearing activities such as jogging or tennis within 48 hours following the intra-articular injection.
Pregnancy & Breastfeeding use
The safety and effectiveness of Hyronate 0.2% Intra-articular Injection have not been established in pregnant women. It is not known if Hyronate 0.2% Intra-articular Injection is excreted in human milk. The safety and effectiveness of Hyronate 0.2% Intra-articular Injection have not been established in lactating mother. The safety and effectiveness of Hyronate 0.2% Intra-articular Injection have not been demonstrated in children.
Contraindication
The drug is contraindicated in patients with known hypersensitivity to hyaluronate preparations. Intra-articular injections are contraindicated in cases of past and present infections or skin diseases in the area of the injection site.
Acute Overdose
No case of over dosage has been reported to date.
Storage Condition
Hyronate injection should be stored in a cool (below 25° C) and dry place and protected from light. Protect from freezing.
Innovators Monograph
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FAQ
What is Hyronate 0.2% Intra-articular Injection used for?
Hyronate 0.2% Intra-articular Injection topical skin medication is used to treat skin ulcers such as bed sores or diabetic foot ulcers, as well as burn wounds, surgical incisions, cuts, abrasions, and other skin irritations. Hyronate 0.2% Intra-articular Injection skin medication is also used to treat dry or scaly skin.
How safe is Hyronate 0.2% Intra-articular Injection?
Hyronate 0.2% Intra-articular Injection as well as are considered safe. It's rarely associated with side effects when applied topically.
How does Hyronate 0.2% Intra-articular Injection work?
Hyronate 0.2% Intra-articular Injection works by pulling in moisture from the environment and the underlying layers of your skin into the epidermis.
What are the common side effects of Hyronate 0.2% Intra-articular Injection?
The common side effects of Hyronate 0.2% Intra-articular Injection are include:
- warmth, pain, redness, stiffness, bruising, or puffiness where the medicine was injected;
- nausea, stomach pain;
- trouble walking;
- swelling in your hands or feet;
- back pain, joint pain, muscle pain;
- numbness or tingly feeling;
- headache, dizziness; or
- runny or stuffy nose, sneezing, sore throat.
How is Hyronate 0.2% Intra-articular Injection given?
Hyronate 0.2% Intra-articular Injection is injected directly into your knee joint. A healthcare provider will give you this injection.
Hyronate 0.2% Intra-articular Injection is usually given once every week for 3 to 5 weeks. Follow your doctor's dosing instructions very carefully.
Who should not take Hyronate 0.2% Intra-articular Injection?
You should not receive a Hyronate 0.2% Intra-articular Injection injection if you have an infection in your knee or in the skin around your knee.
Is Hyronate 0.2% Intra-articular Injection safe during pregnancy?
Hyronate 0.2% Intra-articular Injection also safe to use during pregnant.
Is Hyronate 0.2% Intra-articular Injection safe during breastfeeding?
It is not known whether Hyronate 0.2% Intra-articular Injection topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Is Hyronate 0.2% Intra-articular Injection safe for skin?
Hyronate 0.2% Intra-articular Injection are considered safe. It's rarely associated with side effects when applied topically.
How long take Hyronate 0.2% Intra-articular Injection?
Hyronate 0.2% Intra-articular Injection usually given once every week for 3 to 5 weeks.
How long does Hyronate 0.2% Intra-articular Injection last?
Hyronate 0.2% Intra-articular Injection lasts for about six months or longer in most people.
How much Hyronate 0.2% Intra-articular Injection should I take?
Doses of 120–240 mg per day for at least one month have been shown to significantly increase skin moisture and reduce dry skin in adults.
Does Hyronate 0.2% Intra-articular Injection have long term benefits?
Studies show that long term use is safe, with no reported side effects from Hyronate 0.2% Intra-articular Injection supplementation. Used as a topical skincare ingredient, Hyronate 0.2% Intra-articular Injection is also well tolerated.
Is it OK to use Hyronate 0.2% Intra-articular Injection every day?
Yes, you can even use it twice a day as long as you're applying it to clean, damp skin, then locking it in with a moisturizer and face oil.
What happens if you use too much Hyronate 0.2% Intra-articular Injection?
Too much Hyronate 0.2% Intra-articular Injection can leave skin thirstier, and dehydration lines more prominent.
Does Hyronate 0.2% Intra-articular Injection lighten dark spots?
Hyronate 0.2% Intra-articular Injection can also minimize age spots and prevent any dark spots in the future on your skin.
Can Hyronate 0.2% Intra-articular Injection dry skin?
Hyronate 0.2% Intra-articular Injection is one of the most hydrating ingredients, but if misused,Hyronate 0.2% Intra-articular Injection can actually dry out your skin.
Is Hyronate 0.2% Intra-articular Injection good for pimples?
While Hyronate 0.2% Intra-articular Injection can't fill in visible acne scars, it can help reduce redness and the visible appearance of acne.
Is Hyronate 0.2% Intra-articular Injection good for wrinkles?
Hyronate 0.2% Intra-articular Injection is well known for its skin benefits, especially alleviating dry skin, reducing the appearance of fine lines and wrinkles and speeding up wound healing.
Is Hyronate 0.2% Intra-articular Injection good for hair?
You can use Hyronate 0.2% Intra-articular Injection regardless of your hair type. It'll help your hair follicles lock in moisture.
Can I use Hyronate 0.2% Intra-articular Injection under eyes?
Yes you can.Hyronate 0.2% Intra-articular Injection can help mask darkness under the eyes.
What does Hyronate 0.2% Intra-articular Injection do to your face?
Hyronate 0.2% Intra-articular Injection helps reduce the visibility of fine lines and wrinkles retaining moisture to the skin.
Can Hyronate 0.2% Intra-articular Injection cause facial hair growth?
Hyronate 0.2% Intra-articular Injection is similar to a fertilizer because it can increase hair growth.
What happen If I missed Hyronate 0.2% Intra-articular Injection?
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
What happens if I overdose?
Hyronate 0.2% Intra-articular Injection may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing.call a poison control center right away.
