ISIS 14803 Uses, Dosage, Side Effects and more
ISIS 14803 is a 20-unit antisense phosphorothioate oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and inhibits protein expression in cell culture.
| Trade Name | ISIS 14803 |
| Generic | ISIS 14803 |
| Type | |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in hepatitis (viral, C).
How ISIS 14803 works
ISIS 14803 blocks the synthesis of disease-causing proteins by preventing translation of viral RNA. In the case of hepatits C virus (HCV), an antisense oligodeoxynucleotide directed against a specific HCV sequence effectively inhibits viral gene expression.
