Isomethadone I

Isomethadone I Uses, Dosage, Side Effects, Food Interaction and all others data.

Isomethadone I is used as an opioid antitussive in combination with Oxilofrine. It is marketed in Canada by Valeant under the tradename Cophylac.

Isomethadone I is an opioid which suppresses coughing by central and peripheral mechanisms .

Trade Name Isomethadone I
Generic Normethadone
Normethadone Other Names Desmethylmethadone, Isomethadone I, Normethadone
Type
Formula C20H25NO
Weight Average: 295.426
Monoisotopic: 295.193614429
Groups Approved, Illicit
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Isomethadone I
Isomethadone I

Uses

Isomethadone I is an opioid antitussive used to treat a cough associated with inflamed mucosa.

For use in the treatment of cough when other less potent treatments have failed .

How Isomethadone I works

Isomethadone I activates central opioid receptors in the medulla to supress the cough reflex . It also likely activates peripheral opioid receptors to inhibit signalling by irritant receptors of the airway.

Toxicity

The toxic effects of normethadone are similar to those of other opioids. It can produce respiratory depression, depression of central nervous system function, and constipation .

Food Interaction

  • Avoid alcohol. Ingesting alcohol may cause additive CNS depressive effects.

Innovators Monograph

You find simplified version here Isomethadone I

*** Taking medicines without doctor's advice can cause long-term problems.
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