Isoxsuprine
Isoxsuprine Uses, Dosage, Side Effects, Food Interaction and all others data.
A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
Trade Name | Isoxsuprine |
Availability | Prescription only |
Generic | Isoxsuprine |
Isoxsuprine Other Names | Isoxsuprine |
Related Drugs | amlodipine, Xarelto, nitroglycerin, Brilinta, nifedipine, rivaroxaban, Norvasc, ticagrelor, prazosin, doxazosin |
Weight | 10mg, 20mg, |
Type | Oral tablet |
Formula | C18H23NO3 |
Weight | Average: 301.386 Monoisotopic: 301.167793605 |
Groups | Approved, Withdrawn |
Therapeutic Class | |
Manufacturer | |
Available Country | United States |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Isoxsuprine is a beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease.
Isoxsuprine is also used to associated treatment for these conditions: Arteriosclerosis Obliterans, Buerger's Disease, Cerebrovascular Insufficiency, Raynaud's Phenomenon, Thromboangiitis Obliterans, Peripheral vasodilatation
Food Interaction
No interactions found.Isoxsuprine Drug Interaction
Unknown: amphetamine / dextroamphetamine, amphetamine / dextroamphetamine, epinephrine, epinephrine, spironolactone, spironolactone, amoxicillin, amoxicillin, multivitamin, multivitamin, calcium carbonate, calcium carbonate, multivitamin with minerals, multivitamin with minerals, acetaminophen / butalbital / caffeine, acetaminophen / butalbital / caffeine, acetaminophen, acetaminophen, multivitamin, multivitamin
Isoxsuprine Disease Interaction
Innovators Monograph
You find simplified version here Isoxsuprine
FAQ
What is Isoxsuprine used for?
Isoxsuprine is a drug used as a vasodilator in humans and equines. Isoxsuprine is a β₂ adrenoreceptor agonist that causes direct relaxation of uterine and vascular smooth muscle via β₂ receptors. Isoxsuprine relaxes the uterine smooth muscles and is used for treatment of pre-term labor and dysmenorrhea. It is absorbed in the gastrointestinal system and is excreted in urine.
How safe is Isoxsuprine?
Researchers in this study reported that Isoxsuprine was safe for treating acute pre-term labor and also as a maintenance therapy. Also, it was shown that prophylactic oral Isoxsuprine does not lower the risk of pre-term labor in high-risk, single pregnancies.
How does Isoxsuprine work?
This Isoxsuprine works by relaxing the smooth muscle that surrounds small blood vessels causing vasodilation and potentially increasing blood flow to the hooves.
What are the common side effects of Isoxsuprine?
Common side effects of Isoxsuprine are include:
- weakness.
- dizziness.
- flushing (feeling of warmth)
- upset stomach.
- vomiting.
- stomach pain.
Is Isoxsuprine safe during pregnancy?
This means that it is not known whether Isoxsuprine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
Is Isoxsuprine safe during breastfeeding?
Do not take this Isoxsuprine without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Isoxsuprine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.
Can I drink alcohol with Isoxsuprine?
Isoxsuprine can cause drowsiness, dizziness or faintness. Drinking alcohol with Isoxsuprine can make you faint or feel even more drowsy or dizzy.
Can I drive after talking Isoxsuprine?
Use caution when driving, operating machinery, or performing other hazardous activities. Isoxsuprine may cause dizziness. If you experience dizziness, avoid these activities.
When should I take Isoxsuprine ?
Isoxsuprine is used to relieve the symptoms of central and peripheral vascular diseases such as arteriosclerosis, Buerger's disease, and Raynaud's disease.
When should be taken of Isoxsuprine?
Isoxsuprine is taken by mouth with or without food, usually 3 to 4 times daily or as directed by your doctor.
Can I take Isoxsuprine on empty stomach?
Isoxsuprine comes in the form of tablet to take orally. It is usually taken 3-4 times in a day. It can be taken with food or on an empty stomach. Read the prescription label carefully before starting the medication.
How long does Isoxsuprine take to work?
This revealed a significant increase in distal limb temperature which occurred from 90 to 480 mins after Isoxsuprine administration.
How long does Isoxsuprine take to work?
Isoxsuprine to have a plasma half-life of <3. h with a large apparent volume of distribution.
Who should not take Isoxsuprine?
Older adults should not usually take Isoxsuprine because it is not as safe and effective as other medications that can be used to treat the same condition. if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking Isoxsuprine.
What happen If I suddenly stop taking Isoxsuprine ?
Isoxsuprine should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side-effects. Also, it is not suitable for some people. Inform your doctor before starting Isoxsuprine if you have any bleeding disorder or heart problem. Do not do strenuous activities to avoid premature labour.
What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of Isoxsuprine.
What happens if I overdose?
Seek emergency medical attention if an overdose is suspected. Symptoms of an isoxsuprine overdose include weakness, lightheadedness, fainting, nausea, and vomiting.
Can Isoxsuprine cause hypotension?
Isoxsuprine caused slight maternal hypotension and a transient acidosis, both of which returned to baseline values within 60 minutes.
Is Isoxsuprine safe for the baby?
There are no reports of problems with Isoxsuprine in breastfeeding babies.
Can Isoxsuprine cause tachycardia?
The important adverse reactions of Isoxsuprine are tachycardia and orthostatic hypotension, but they occur only at high dosages.