Itchfre

Itchfre Uses, Dosage, Side Effects, Food Interaction and all others data.

Menthol primarily activates the cold-sensitive TRPM8 receptors in the skin. Menthol, after topical application, causes a feeling of coolness due to stimulation of 'cold' receptors by inhibiting Ca++ currents of neuronal membranes. It may also yield analgesic properties via kappa-opioid receptor agonism.

Pramocaine reversibly binds and inhibits voltage gated sodium channels on neurons decreasing sodium permeability into the cell. This stabilizes the membrane and prevents ionic fluctuations needed for depolarization stopping any action potential propagation.

Menthol and pramoxine: Each of these agents elicits local anesthetic effects.

Itchfre
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Itchfre
Generic	Menthol + Pramoxine Hydrochloride
Weight	1% + 1%
Type	Cream
Therapeutic Class	Local Antipruritic, Topical Analgesics
Manufacturer	Pacific Pharmaceuticals Ltd
Available Country	Bangladesh
Last Updated:	September 19, 2023 at 7:00 am

Uses

Pain and Itching: For temporary relief of pain and itch associated with minor skin irritations, minor cuts, minor burns, minor sunburns, scrapes, or insect bites; may also be used for rashes due to poison ivy, oak, or sumac.

Dosage

Itchfre dosage

Adult: Apply topically to affected area up to 3-4 times daily.Child:

<2 years: Safety and efficacy not established
>2 years: Apply topically to affected area up to 3-4 times daily

Side Effects

Redness, irritation, swelling or pain.

Precaution

For external use only. Avoid contact with eyes Do not use in the eyes or mucous membranes Not for prolonged use Do not apply to large areas of the body. Discontinue if symptoms persist for >7 days or clear up and occur again within a few days. Discontinue if redness, irritation, swelling, or pain persists or increases

Interaction

There are no known drug interactions and none well documented.

Pregnancy & Breastfeeding use

Pregnancy Category A. Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).