Jizinc Uses, Dosage, Side Effects and more
Jizinc is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Jizinc is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.
Although it has been nasally administered for treating the common cold, this route of administration has been associated with some cases of anosmia , , , .
Studies show that zinc may be better absorbed in humans in the gluconate form , , however, results from other studies may vary , [L27280].
| Trade Name | Jizinc |
| Generic | Zinc gluconate |
| Zinc gluconate Other Names | Zinc gluconate |
| Type | Syrup |
| Formula | C12H22O14Zn |
| Weight | Average: 455.67 Monoisotopic: 454.030097 |
| Protein binding | Please refer to DrugBank entry Zinc |
| Groups | Approved, Vet approved |
| Therapeutic Class | |
| Manufacturer | Mathis Pharma |
| Available Country | India |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Jizinc is an ingredient found in a variety of supplements and vitamins.
Jizinc is mainly indicated in conditions like zinc deficiency, and can also be administered in adjunctive therapy as an alternative drug of choice in diarrhea .
Jizinc is also used to associated treatment for these conditions: Zinc Deficiency
How Jizinc works
Although the mechanism of action is not completely known, zinc supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV) .
Toxicity
Nausea, vomiting, diarrhea, and mouth irritation have been reported in patients ingesting zinc gluconate tablets that were dissolved in the mouth for management the common cold .
Zinc crosses the placenta and is found the cord blood and placenta. Fetal concentrations are regulated by the placenta .
For more information, refer to Please refer to DrugBank entry Zinc.
Acute: 1290 mg/kg in mouse
Food Interaction
- Avoid milk and dairy products. Separate the use of zinc from these products by at least 2 hours before administration. Separate for 2 hours after administration if these products also contain phosphorus.
- Do not take with bran and high fiber foods. For optimal absorption, take zinc at least 2 hours before or after eating high-fiber foods.
- Take on an empty stomach. Take at least 1 hour before and 2 hours after eating for optimal absorption. Zinc can be taken with food to reduce gastrointestinal upset.
Volume of Distribution
Stored primarily in skeletal muscle and bone .
Elimination Route
Please refer to DrugBank entry Zinc
Half Life
280 days
Clearance
Please refer to DrugBank entry Zinc
Elimination Route
Feces and urine
