Kanarb

Kanarb Uses, Dosage, Side Effects, Food Interaction and all others data.

Kanarb is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Kanarb was initially approved September 9th, 2010 in South Korea and is marketed under the brand name Kanarb by Boryung Pharmaceuticals.

Kanarb is a selective angiotensin receptor 1 (AR1) inhibitor . It acts to lower blood pressure by inhibiting vasoconstriction

Kanarb
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Uses during Pregnancy
Uses during Breastfeeding
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Trade Name	Kanarb
Generic	Fimasartan
Fimasartan Other Names	Fimasartan
Type
Formula	C₂₇H₃₁N₇OS
Weight	Average: 501.65 Monoisotopic: 501.23107982
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Kanarb is an angiotensin II receptor antagonist (ARB) used to treat hypertension and heart failure.

Used for the treatment of hypertension and heart failure .

Kanarb is also used to associated treatment for these conditions: Hypertension,Essential

How Kanarb works

Angiotensin II activates AR1 leading to vasoconstriction and increased noradrenaline release which further increases vasoconstriction via action at α1-adrenergic receptors . It also stimulates secretion of aldosterone which acts to increase sodium and water reabsorption in the renal tubules . Kanarb bind to and antagonizes AR1 preventing vasoconstriction and reducing aldosterone secretion to increase natriuresis leading to a reduction in blood volume. Together these effects produce an anti-hypertensive effect.