Kendall's Compound E

Kendall's Compound E Uses, Dosage, Side Effects, Food Interaction and all others data.

A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Kendall's Compound E itself is inactive. It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)

Trade Name Kendall's Compound E
Availability Prescription only
Generic Cortisone
Cortisone Other Names Cortisona, Cortisone, Cortisonum, Kendall's compound E, Kortison, Reichstein's substance Fa
Related Drugs Humira, Cosentyx, Promacta, aspirin, prednisone, ibuprofen, meloxicam, naproxen, diclofenac ophthalmic, Cymbalta
Type
Formula C21H28O5
Weight Average: 360.444
Monoisotopic: 360.193674006
Groups Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Kendall's Compound E
Kendall's Compound E

Kendall's Compound E Cholesterol interaction

[Moderate] Corticosteroids may elevate serum triglyceride and LDL cholesterol levels if used for longer than brief periods.

Patients with preexisting hyperlipidemia may require closer monitoring during prolonged corticosteroid therapy, and adjustments made accordingly in their lipid-lowering regimen.

Kendall's Compound E Hypertension interaction

[Moderate] Corticosteroids may cause hypernatremia, hypokalemia, fluid retention, and elevation in blood pressure.

These mineralocorticoid effects are most significant with fludrocortisone, followed by hydrocortisone and cortisone, then by prednisone and prednisolone.

The remaining corticosteroids, betamethasone, dexamethasone, methylprednisolone, and triamcinolone, have little mineralocorticoid activities.

However, large doses of any corticosteroid can demonstrate these effects, particularly if given for longer than brief periods.

Therapy with corticosteroids should be administered cautiously in patients with preexisting fluid retention, hypertension, congestive heart failure, and

Dietary sodium restriction and potassium supplementation may be advisable.

Innovators Monograph

You find simplified version here Kendall's Compound E

*** Taking medicines without doctor's advice can cause long-term problems.
Share