Kofnix-SR

Kofnix-SR Uses, Dosage, Side Effects, Food Interaction and all others data.

Kofnix-SR Citrate belongs to the anti-cough medicines of central action. It exerts expectorant, moderate bronchodilating and anti-inflammatory action. Kofnix-SR Citrate also increases the spirometery indexes and blood oxygenation. It is safe and non-sedating which is neither chemically nor pharmacologically related to opium alkaloids. The active metabolites of Kofnix-SR Citrate have also antitussive action.

Trade Name Kofnix-SR
Generic Butamirate
Butamirate Other Names Butamirate
Type
Formula C18H29NO3
Weight Average: 307.434
Monoisotopic: 307.214743798
Groups Experimental
Therapeutic Class Cough suppressant
Manufacturer
Available Country Bangladesh
Last Updated: September 19, 2023 at 7:00 am
Kofnix-SR
Kofnix-SR

Uses

Kofnix-SR Citrate is used for acute cough of any etiology, suppression of pre-& post-operative cough in surgery & bronchoscopy and suppression of whooping cough.

Kofnix-SR is also used to associated treatment for these conditions: Cough

Dosage

Kofnix-SR dosage

Tablet:

  • Adult: 2-3 tablets daily at 8 to 12 hours intervals,
  • Adolescents over 12 years old: 1-2 tablets daily.

Syrup:

  • Children (3-6 years): 5 ml 3 times daily,
  • Children (6-12 years): 10 ml 3 times daily,
  • Adolescent: 15 ml 3 times daily,
  • Adult: 15 ml 4 times daily.

PediatricDrops:

  • Children (1-3 years): 0.75 ml 4 times daily,
  • Children (2 months-1 year): 0.50 ml 4 times daily.

Side Effects

Tolerance of Kofnix-SR Citrate is good. Adverse reactions such as rash, nausea, diarrhea and vertigo have been observed in a few rare cases, resolving after dose reduction or treatment withdrawal.

Precaution

Avoid simultanous administration of expectorants. Minor influence on the ability to drive & use machines. Avoid during pregnancy (1st 3 months) & lactation.

Tablet: Rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption.

Syrup: Sorbitol: Rare hereditary problems of fructose intolerance. Contains ethanol.

Interaction

Avoid use with expectorants.

Pregnancy & Breastfeeding use

Kofnix-SR Citrate should not be used during the first trimester of pregnancy. During the remainder of pregnancy, it can be used if indicated by a physician but with caution. As a general rule, for safety reasons, in the absence of data on elimination of the active substance in breast milk, the benefits of Kofnix-SR Citrate administration during breast feeding should be carefully weighed against the risks.

Contraindication

Kofnix-SR Citrate is contraindicated in patients with known hypersensitivity to any component of the formulation.

Acute Overdose

Accidental overdose with Kofnix-SR Citrate can cause the following symptoms: drowsiness, nausea, vomiting, diarrhea, loss of balance and hypotension. Standard emergency procedures should be followed: activated charcoal, saline laxatives and standard cardio-respiratory resuscitation.

Storage Condition

Do not store above 30 0 C. Keep away from light and out of the reach of children.

Innovators Monograph

You find simplified version here Kofnix-SR

*** Taking medicines without doctor's advice can cause long-term problems.
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