Kolbam
Kolbam Uses, Dosage, Side Effects, Food Interaction and all others data.
A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. [PubChem]Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid synthesis disorders due to single enzyme defects, and for peroxisomal disorders (such as Zellweger syndrome).
| Trade Name | Kolbam |
| Generic | Cholic Acid |
| Cholic Acid Other Names | Cholic Acid |
| Type | |
| Formula | C24H40O5 |
| Weight | Average: 408.5714 Monoisotopic: 408.28757439 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | Austria, Belgium, Bulgaria, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, United Kingdom |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Kolbam is a bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function.
Oral cholic acid is indicated for: treatment of bile acid synthesis disorders due to single enzyme defects; and as adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea or complications from decreased fat soluble vitamin absorption.
Kolbam is also used to associated treatment for these conditions: Inborn error in primary bile acid synthesis, Peroxisomal Disorders
Food Interaction
- Take separate from antacids. Take at least 1 hour before or 4-6 hours after aluminum-containing antacids.
- Take with food.
Innovators Monograph
You find simplified version here Kolbam
