Kolpicortin
Kolpicortin Uses, Dosage, Side Effects, Food Interaction and all others data.
Kolpicortin is a muscle relaxant. It blocks nerve impulses (or pain sensations) that are sent to the brain.
| Trade Name | Kolpicortin |
| Availability | Discontinued |
| Generic | Chlorphenesin |
| Chlorphenesin Other Names | Chlorphenesin, Chlorphénésine, Chlorphenesinum, Clorfenesina |
| Related Drugs | cyclobenzaprine, tizanidine, diazepam, methocarbamol, Flexeril, Soma |
| Type | |
| Formula | C9H11ClO3 |
| Weight | Average: 202.635 Monoisotopic: 202.039671925 |
| Groups | Approved, Experimental |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Kolpicortin is a phenol ether used to treat painful muscular conditions.
Used, along with rest and physical therapy, to treat injuries and other painful muscular conditions. Investigated for use in trigeminal neuralgia (tic douloureux), a neuropathic disorder characterized by severe facial pain. Was investigated as a modulator of histamine release.
Kolpicortin is also used to associated treatment for these conditions: Muscle Spasms
How Kolpicortin works
The mechanism of action of chlorphenesin is not well defined, and its effects are measured mainly by subjective responses. It is known that chlorphenesin acts in the central nervous system (CNS) rather than directly on skeletal muscle.
Toxicity
Symptoms of a chlorphenesin overdose include drowsiness and nausea.
Food Interaction
No interactions found.[Moderate] GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents.
Use in combination may result in additive central nervous system depression and
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol.
Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
Kolpicortin Drug Interaction
Major: tramadol, tramadolUnknown: amoxicillin / clavulanate, amoxicillin / clavulanate, glucose, glucose, acetaminophen, acetaminophen, tiotropium, tiotropium, thiamine, thiamine, riboflavin, riboflavin, ascorbic acid, ascorbic acid, cholecalciferol, cholecalciferol, zinc sulfate, zinc sulfate
Elimination Route
Rapid and complete.
Half Life
2.3-5 hours
Innovators Monograph
You find simplified version here Kolpicortin
