L-Lysine

L-Lysine Uses, Dosage, Side Effects, Food Interaction and all others data.

L-Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. L-Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.

Insures the adequate absorption of calcium; helps form collagen ( which makes up bone cartilage & connective tissues); aids in the production of antibodies, hormones & enzymes. Recent studies have shown that L-Lysine may be effective against herpes by improving the balance of nutrients that reduce viral growth. A deficiency may result in tiredness, inability to concentrate, irritability, bloodshot eyes, retarded growth, hair loss, anemia & reproductive problems.

Trade Name L-Lysine
Availability Over the counter
Generic Lysine
Lysine Other Names L-Lysin, L-Lysine, Lysina, Lysine, Lysine acid, Lysinum
Related Drugs acyclovir, valacyclovir, Valtrex, turmeric, Zovirax, Ginkgo Biloba, saw palmetto
Type
Formula C6H14N2O2
Weight Average: 146.1876
Monoisotopic: 146.105527702
Groups Approved, Nutraceutical
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
L-Lysine
L-Lysine

Uses

L-Lysine is an amino acid commonly found as a component of total parenteral nutrition.

Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.

L-Lysine is also used to associated treatment for these conditions: Weight Loss, Weight Gain, Amino acid supplementation

How L-Lysine works

Proteins of the herpes simplex virus are rich in L-arginine, and tissue culture studies indicate an enhancing effect on viral replication when the amino acid ratio of L-arginine to lysine is high in the tissue culture media. When the ratio of L-lysine to L-arginine is high, viral replication and the cytopathogenicity of herpes simplex virus have been found to be inhibited. L-lysine may facilitate the absorption of calcium from the small intestine.

Food Interaction

No interactions found.

Elimination Route

Absorbed from the lumen of the small intestine into the enterocytes by an active transport process

Innovators Monograph

You find simplified version here L-Lysine

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http://classyfire.wishartlab.com/tax_nodes/C0000489
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http://classyfire.wishartlab.com/tax_nodes/C0001137
http://classyfire.wishartlab.com/tax_nodes/C0001205
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0003940
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https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18019
http://www.genome.jp/dbget-bin/www_bget?cpd:C00047
http://www.hmdb.ca/metabolites/HMDB0003405
http://www.genome.jp/dbget-bin/www_bget?drug:D02304
http://www.genome.jp/dbget-bin/www_bget?cpd:C00047
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5962
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46504770
https://www.chemspider.com/Chemical-Structure.5747.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=217367
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=6536
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=18019
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL8085
https://zinc.docking.org/substances/ZINC000001532522
http://www.pharmgkb.org/drug/PA450280
https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/LYS
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/lly_0166.shtml
https://en.wikipedia.org/wiki/Lysine
*** Taking medicines without doctor's advice can cause long-term problems.
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