L-Menthol Kozakai M

L-Menthol Kozakai M Uses, Dosage, Side Effects, Food Interaction and all others data.

Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used to relieve minor throat irritations.

Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Menthol induces a cooling sensation on the skin upon inhalation, oral ingestion, or topical application by stimulating the cold-sensitive receptors expressed on the skin, without actually causing a drop in the skin temperature.

Trade Name L-Menthol Kozakai M
Generic Levomenthol
Levomenthol Other Names L-menthol, Levomenthol, Lévomenthol, Levomentholum, Levomentol, Mentol
Type
Formula C10H20O
Weight Average: 156.2652
Monoisotopic: 156.151415262
Groups Approved
Therapeutic Class
Manufacturer
Available Country Japan
Last Updated: September 19, 2023 at 7:00 am
L-Menthol Kozakai M
L-Menthol Kozakai M

How L-Menthol Kozakai M works

Menthol primarily activates the cold-sensitive TRPM8 receptors in the skin. Menthol, after topical application, causes a feeling of coolness due to stimulation of 'cold' receptors by inhibiting Ca++ currents of neuronal membranes. It may also yield analgesic properties via kappa-opioid receptor agonism.

Toxicity

Menthol, DL: ORAL (LD50): Acute: 2900 mg/kg [Rat], 3100 mg/kg [Mouse]. DERMAL (LD50): Acute: 5001 mg/kg Rabbit.

Food Interaction

No interactions found.

Innovators Monograph

You find simplified version here L-Menthol Kozakai M

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0000012
http://classyfire.wishartlab.com/tax_nodes/C0000259
http://classyfire.wishartlab.com/tax_nodes/C0001549
http://classyfire.wishartlab.com/tax_nodes/C0001401
http://classyfire.wishartlab.com/tax_nodes/C0001563
http://classyfire.wishartlab.com/tax_nodes/C0002647
http://classyfire.wishartlab.com/tax_nodes/C0001292
http://classyfire.wishartlab.com/tax_nodes/C0004150
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:15409
http://www.genome.jp/dbget-bin/www_bget?cpd:C00400
http://www.lipidmaps.org/data/LMSDRecord.php?LMID=LMPR0102090001
http://www.hmdb.ca/metabolites/HMDB0003352
http://www.genome.jp/dbget-bin/www_bget?drug:D00064
http://www.genome.jp/dbget-bin/www_bget?cpd:C00400
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=16666
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46506513
https://www.chemspider.com/Chemical-Structure.15803.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50318482
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=236388
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=15409
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL470670
https://zinc.docking.org/substances/ZINC000001482164
http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000876
http://www.pharmgkb.org/drug/PA164776605
http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2430
https://www.drugs.com/cdi/menthol-cream.html
https://en.wikipedia.org/wiki/Menthol
*** Taking medicines without doctor's advice can cause long-term problems.
Share