La Prairie Anti-Aging Day
La Prairie Anti-Aging Day Uses, Dosage, Side Effects, Food Interaction and all others data.
Avobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as wide spectrum sunscreens. Avobenzone is very sensitive to light, to increase its stability and duration of action, photostablizers are added in the sunscreen product. Avobenzone has an absorption maximum of 357 nm. Sunscreens containing avobenzone is indicated for providing protection from the sun. In addition to limiting the skin's exposure to the sun, using sunscreen agents may help reduce long-term sun damage such as premature aging of the skin and skin cancer.
Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and decrease the risk of percutaneous absorption. Its use in pharmaceutical and cosmetic formulations is approved by FDA.
Acts as a photoprotective agent that protects the skin by preventing and minimizing the damaging effects of ultraviolet (UV) rays of natural light. The cellular effects of UV irradiation include DNA damage, cell cycle arrest, immunological depression, apoptosis, and transcriptional changes .
Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other UV filters. Octyl salicylate appears to have a good safety profile. It covers wavelength in the range 295-315 nm, peak at 307-310 nm.
It is an ester of salicylic acid and 2-ethylhexanol. The salicylate portion of the molecule absorbs ultraviolet light to protect skin from the harmful effects of exposure to sunlight, while the ethylhexanol portion functions as an emollient.
Data not found.
Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin damage from prolonged sun exposure. Octocrylene is also often combined with avobenzone, another common sunscreen ingredient often appearing on ingredient labels. Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and skin care products, but the concentrations of this ingredient are usually limited to no more than 10 or 12 percent. However, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend to a variety of other products, like hair spray, tannin oil, BB cream, conditioner, and CC cream, among others. Octocrylene may cause contact and photocontact allergy.
| Trade Name | La Prairie Anti-Aging Day |
| Generic | Avobenzone + octinoxate + octisalate + octocrylene |
| Type | Cream |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | United States |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Avobenzone is a sunscreen agent found in sunscreens that absorbs UV rays.
Sun protection factor, added in the sunscreen products for its wide spectrum ultraviolet absorption properties.
Octinoxate is a sunscreen agent found in sunscreens that absorbs UV rays.
As an active ingredient in sunscreens and lip balms. Used for protection against damaging effects of sun rays.
Ingredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer.
Octocrylene is a sunscreen agent found in sunscreens that absorbs UV rays.
In the US, Octocrylene has been evaluated by the FDA and is considered safe for use up to 10% in the formula. Similarly, the EU allows its use up to 10% in a formula while Health Canada allows a maximum use level of 12%.
La Prairie Anti-Aging Day is also used to associated treatment for these conditions: SunburnSunburnSunburnSunburn
How La Prairie Anti-Aging Day works
It blocks UVA I, UVA II, and UVB wavelengths, thereby limiting the impact of UV rays on skin. Diminish the penetration of ultraviolet (UV) light through the epidermis by absorbing UV radiation within a specific wavelength range. The amount and wavelength of UV radiation absorbed are affected by the molecular structure of the sunscreen agent.
Absorbs UV-B (predominantly) and UV-A rays while accumulating in the outermost layer of the epidermis. Like any other photoprotective agents, octinoxate prevents the damage to cells and deoxyribonucleic acid (DNA) by reducing the p53 protein expression following UV exposure and also increases the skin's tolerability to UV rays .
Chemical sunscreen, it acts through absorption of UVB light and not UVA.
Octocrylene is an effective oil soluble liquid UV‐B filter. It has excellent dissolving properties for crystalline UV filters. Due to its outstanding photostability it is used as photostabilizer. Conjugated acrylate portion absorbs UVB and short-wave UVA (ultraviolet) rays with wavelengths in the range of 280-320 nm which protects the skin from direct DNA damage. The ethylhexanol portion is a fatty alcohol, which functions as an emollient due to it's hydrophobicity.
Toxicity
A minimum toxic dose has not been established. Significant toxicity is not expected
Slightly hazardous in case of skin contact, eye contact, ingestion and inhalation. Octinoxate may form reactive singlet oxygen species and induce anti-estrogenic effects . UV-induced molecular breakdown of octinoxate may interfere with cellular processes or induce oxidative damage in human skin . The NOAEL (no observed adverse effect level) is 450 mg/kg bw/day for fertility and reproductive performance, for systemic parental and developmental toxicity in Wistar rats .
LD50, (oral, rat): > 5000 mg/Kg. LD50 (dermal, rabbit): > 5000 mg/Kg.
Octocrylene is one of those ingredients that can be absorbed into the skin and some studies have shown that it may promote generation of potentially harmful free radicals when exposed to light. Since free radicals can damage DNA, there is concern that this ingredient might have contributed to an increased incidence of melanoma in sunscreen-users compared to non-users.
Volume of Distribution
Intended for local use only, no systemic absorption.
Ecamsule is only used topically, it not absorbed.
Elimination Route
Can be systemically absorbed after skin application, being found in the deeper layers of the stratum corneum as well as urine, plasma, and breast milk . The mean maximum plasma concentration detected after application of 2mg/cm2 sunscreen was 7ng/mL in women and 16ng/mL in men .
Intended for local use only, no systemic absorption.
Ecamsule is used topically, it not absorbed or metabolized.
Half Life
Intended for local use only, no systemic absorption.
Ecamsule is only used topically, it does not have half life
Clearance
Intended for local use only, no systemic absorption.
Ecamsule is used topically, it not absorbed or metabolized.
Elimination Route
Can be detected in urine in unchanged form .
Intended for local use only, no systemic absorption.
Ecamsule is used topically, it not absorbed.
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