Lacril

Lacril Uses, Dosage, Side Effects, Food Interaction and all others data.

Lacril is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. Lacril is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes .

Temporarily relieves burning and irritation due to dryness of the eye or from exposure to wind or sun.Lubricates the eyes and helps protect against further eye irritation/dryness .

Trade Name Lacril
Generic Polyvinyl alcohol
Polyvinyl alcohol Other Names Alcohol polivinílico, Polyvinyl alcohol
Type
Groups Approved
Therapeutic Class
Manufacturer
Available Country Colombia, Denmark, Ecuador, Peru
Last Updated: September 19, 2023 at 7:00 am
Lacril
Lacril

Uses

Lacril is a compound used as an ophthalmic lubricant.

For use as a lubricant to prevent further irritation or to relieve dryness of the eye(s) .

Lacril is also used to associated treatment for these conditions: Dry Eyes, Eye lubrication

How Lacril works

As a synthetic resin with hydrophilic properties, it increases the persistence of tear film and therefore lubricates and soothes dry/irritated eyes .

Toxicity

The oral acute toxicity of PVOH (LD50) in rats and mice are 20 g/kg and 14.7 g/kg, respectively . Adverse effects include eye pain and changes of vision, and redness or irritation of the eye .

Mild stinging or irritation of the eye, crusting of eyelid, eye pain, ocular hyperaemia, eye pruritus, foreign body sensation, eye discharge, and increased lacrimation may also occur .

Food Interaction

No interactions found.

Volume of Distribution

This drug does not accumulate in the body when administered orally .

Elimination Route

Lacril is poorly absorbed from gastrointestinal tract, and readily eliminated from the body .

Half Life

When injected intravenously, polyvinyl alcohol has a half-life of 90 min .

Intraocularly, in eye drop form, the half-life is 7.2 minutes .

Innovators Monograph

You find simplified version here Lacril

*** Taking medicines without doctor's advice can cause long-term problems.
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