Laxitol 10 gm/15 ml Oral Solution
Laxitol 10 gm/15 ml Oral Solution Uses, Dosage, Side Effects, Food Interaction and all others data.
| Trade Name | Laxitol 10 gm/15 ml Oral Solution |
| Generic | Lactitol Monohydrate |
| Weight | 10 gm/15 ml |
| Type | Oral Solution |
| Therapeutic Class | Osmotic purgatives |
| Manufacturer | Eskayef Pharmaceuticals Ltd. |
| Available Country | Bangladesh |
| Last Updated: | September 24, 2024 at 5:38 am |
Uses
Laxitol 10 gm/15 ml Oral Solution is indicated in chronic idiopathic constipation (CIC), acute and chronic portal systemic encephalopathy.Dosage
Laxitol 10 gm/15 ml Oral Solution dosage
Lactitol can be mixed with hot or cold beverages, puddings etc. Dosage will require adjustment to obtaine one daily bowel movement in constipated patients and two daily bowel movements in patients with portal systemic encephalopathy. In constipation: In adult: The initial daily dosage should be 20 g taken in a single dose with the morning or evening meal. After a few days, a daily dose of 10 g may be sufficient. Children: The mean dosage is 0.25 g/kg body weight daily. 1 to 6 years: 2.5 to 5 gm 6 to 12 years: 5 to 10 gm 12 to 16 years: 10 to 20 gm The effect of lactitol has been found mostly to occur within a few hours after intake. But in some cases the first laxative response may be delayed until the second or third day of administration. Therefore patients should be advised to maintain an adequate daily fluid intake. In portal systemic encephalopathy: The dose should be adjusted according to the severity of the patient’s disease and their individual response. The initial recommended dose is 0.5 to 0.7 gm/kg body weight daily, divided into three daily doses with meals.Side Effects
At the start of the treatment with lactitol may produce abdominal discomforts such as flatulence, pain, cramps or sensation of fullness. Such effects tend to diminish or disappear after a few days of regular intake of Lactitol. Occasionally, nausea or anal pruritus has been reported in some cases.Precaution
Elderly or debilitated patients receiving long-term treatment with lactitol should have their serum electrolytes monitored regularly. As for all laxatives, pre-existing fluid or electrolyte imbalance should be corrected before starting treatment with lactitol. Following treatment of Lactitol, hydrogen may accumulate in the bowel. Patients who need to undergo electrocauterisation procedure should therefore have a thorough bowel cleansing with a non-fermentable solution. Lactitol is not recommended in case s of ileostomy or colostomy. Prolonged use of laxatives without interruption should be avoided.Interaction
Antacids and neomycin should not be given simultaneously with Lactitol to cirrhotic patients with portal systemic encephalopathy. Lactitol may increase potassium loss caused by other drugs e.g. thiazide diuretics, corticosteroids, carbenoxolone, amphotericin B and it may enhance the risk of toxic effects of glycosides in patients receiving concomitant therapy.Pregnancy & Breastfeeding use
Lactitol is minimally absorbed systemically following oral administration, and it is unknown whether maternal use will result in fetal exposure to the drug. There are no data on the presence of lactitol in human or animal milk, the effects on the breastfed infant, or the effects on milk production.Contraindication
Patients with known hypersensitivity to any of the ingredients of this preparation.Storage Condition
Store in a cool, dry place and away from light. Keep out of reach of children.Innovators Monograph
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