Laxiza Orange Lemon Flav

Laxiza Orange Lemon Flav Uses, Dosage, Side Effects, Food Interaction and all others data.

In the colon it is broken down to short chain organic acids and increases osmotic pressure in the colon, thereby causing an increase in the stool water content and stool volume.

Laxiza Orange Lemon Flav helps to facilitate bowel movements by drawing water into the gastrointestinal tract. The oral administration of lactitol may reduce the absorption of concomitant medications - other oral medications should be administered at least 2 hours before or 2 hours after lactitol.

Trade Name Laxiza Orange Lemon Flav
Availability Prescription only
Generic Lactitol
Lactitol Other Names Lactitol, Lactitolum
Related Drugs Trulance, Motegrity, prucalopride, plecanatide, Pizensy
Type Powder
Formula C12H24O11
Weight Average: 344.3124
Monoisotopic: 344.13186161
Protein binding

As it undergoes little-to-no systemic absorption, lactitol is unlikely to be subject to protein binding.

Groups Approved, Investigational
Therapeutic Class Osmotic purgatives
Manufacturer Tas Med India Pvt Ltd
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Laxiza Orange Lemon Flav
Laxiza Orange Lemon Flav

Uses

Constipation, Hepatic encephalopathy

Laxiza Orange Lemon Flav is also used to associated treatment for these conditions: Constipation, Hepatic Encephalopathy (HE), Occasional Constipation, Chronic idiopathic constipation (CIC)

How Laxiza Orange Lemon Flav works

Laxiza Orange Lemon Flav is an osmotic laxative - it exerts its pharmacologic effect by creating a hyperosmotic environment within the small intestine. The osmotic effect generated by lactitol draws water into the small intestine, which loosens stools and ultimately facilitates bowel movements.

Dosage

Laxiza Orange Lemon Flav dosage

2 teaspoonfuls (20 gm) once or twice daily with plenty of water

Side Effects

Abdominal distension, flatulance and abdominal cramp.

Toxicity

The LD50 is 23 g/kg in mice and >30 g/kg in rats.

Experience with acute overdosage is limited, but is likely to involve significant gastrointestinal upset and diarrhea consistent with the pharmacologic profile of lactitol. Overdosage should be managed with symptomatic and supportive measures, where necessary.

Precaution

Lactose intolerance.

Food Interaction

  • Take with food. The manufacturer recommends administration with meals.

[Moderate] ADJUST DOSING INTERVAL: Laxiza Orange Lemon Flav may decrease the absorption of concomitantly administered oral medications.

MANAGEMENT: Laxiza Orange Lemon Flav should be administered at least 2 hours before or 2 hours after concomitant oral medications.

Volume of Distribution

Data regarding the volume of distribution of lactitol are unavailable.

Elimination Route

In healthy subjects under fed conditions, oral administration of 20 grams of lactitol resulted in a mean Tmax of 3.6 ± 1.2 hours, Cmax of 776 ± 253 ng/mL, and a mean AUC of 6,019 ± 1,771 ng*hr/mL.

Half Life

The average half-life of orally administered lactitol is 2.4 hours.

Clearance

Data regarding the clearance of lactitol are unavailable.

Elimination Route

Laxiza Orange Lemon Flav is not absorbed in the gastrointestinal tract to any significant extent. The vast majority of an ingested dose is likely degraded into organic acids in the colon and eliminated in the feces.

Pregnancy & Breastfeeding use

Pregnancy Category - Not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Contraindication

Patients with known hypersensitivity to any of the active substance. Gastro-intestinal obstruction. Galactosaemia.

Innovators Monograph

You find simplified version here Laxiza Orange Lemon Flav

*** Taking medicines without doctor's advice can cause long-term problems.
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