Lipoprotein Outer Surface A Borrelia Burgdorferi Antigen Uses, Dosage, Side Effects and more
Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant.
OspA lipoprotein is a single polypeptide chain of 270 amino acids. It is a vaccination used to prevent Lyme Disease.
| Trade Name | Lipoprotein Outer Surface A Borrelia Burgdorferi Antigen |
| Generic | Lyme disease vaccine (recombinant OspA) |
| Lyme disease vaccine (recombinant OspA) Other Names | Lipoprotein OspA antigen recombinant, Lipoprotein outer surface a borrelia burgdorferi antigen, OspA lipoprotein |
| Type | |
| Formula | C1198H2012N322O422S2 |
| Weight | 27743.1 Da |
| Groups | Approved, Withdrawn |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
For prophylactic treatment of Lyme Disease
How Lipoprotein Outer Surface A Borrelia Burgdorferi Antigen works
OspA lipoprotein, an outer surface protein of the bacteria Borrelia burgdorferi sensu stricto ZS7, is used to stimulate the production of specific antibodies against B. burgdorferi. It is used as a vaccination against Lyme Disease, a disease carried by ticks.
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
