Listerine Tartar Control Mouthwash

Listerine Tartar Control Mouthwash Uses, Dosage, Side Effects, Food Interaction and all others data.

A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)

Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes.

Zinc chloride was granted FDA approval before 26 June 1986.

Zinc is a cofactor in many enzymes and mediates a number of catalytic, structural, and regulatory roles in the body. It has a wide therapeutic index and long duration of action, as most zinc in the body is reabsorbed. Patients should be counselled regarding the risk of administration in patients with severe kidney dysfunction.

Listerine Tartar Control Mouthwash
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Listerine Tartar Control Mouthwash
Generic	Thymol + Alcohol + Zinc Chloride
Weight	12.78mg, (95%v/v) 4.54ml, 18.00mg
Type	Liquid
Therapeutic Class
Manufacturer	Johnson & Johnson (pty) Ltd
Available Country	South Africa, Nigeria
Last Updated:	September 19, 2023 at 7:00 am

Uses

Thymol is an essential oil found in various over-the-counter antibacterial and antifungal products.

Zinc chloride is a medication used to treat zinc deficiencies and associated symptoms and also in total parenteral nutrition.

Zinc chloride injections are indicated for use total parenteral nutrition to maintain zinc serum levels and prevent deficiency syndromes.

Listerine Tartar Control Mouthwash is also used to associated treatment for these conditions: Arthritis, Backache, Contusions, Joint Diseases, Joint Pain, Muscle Stiffness, Muscle Strain, Muscular Fatigue, Pain, Nerve, Plaque, Dental, Soreness, Muscle, Sprains, Skin disinfectionDietary Supplementations

How Listerine Tartar Control Mouthwash works

Zinc performs catalytic, structural, and regulatory roles in the body. Zinc is a component of approximately 3000 human proteins.

Zinc is cytoprotective against reactive oxygen species mediated apoptosis through the action of metallothioneins.

In a promyelocytic leukemia cell line, zinc enhances the up-regulation of A20 mRNA, which, via the TRAF pathway, decreases NF-kappaB activation, leading to decreased gene expression and generation of TNF-α, IL-1β, and IL-8 .

In patients with diarrhea, zinc restores mucosal barrier integrity, restores enterocyte brush-border enzyme activity, promotes the production of antibodies, and promotes the production of circulating lymphocytes against intestinal pathogens. Zinc also directly affects ion channels as a potassium channel blocker of cAMP-mediated chlorine secretion.

Zinc deficiency decreases thymulin, inhibiting T-helper cell maturation and decreased Th-1 cytokines like IL-2. Decreased IL-2 decreases the activity of NK cells and CD8+ T cells. Zinc deficiency also leads to the generation of CD4+ T cells, decreased NF-κB activation, decreased phosphorylation of IκB, and decreased binding of NF-κB to DNA.

Toxicity

Patients experiencing and overdose may present with hypotension, pulmonary edema, diarrhea, vomiting, jaundice, and oligouria. Overdose can be managed through symptomatic and supportive treatment which may include sodium calcium edetate and analgesics.

The oral LD₅₀ in mice is 329 mg/kg and in rats is 350 mg/kg.

Elimination Route

Zinc is approximately 33% orally bioavailable in humans but bioavailability can vary between patients and depending on current zinc levels. Further data regarding the pharmacokinetics of zinc chloride are not readily available.