Livocab direkt

Livocab direkt Uses, Dosage, Side Effects, Food Interaction and all others data.

Livocab direkt is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Livocab direkt was discovered at Janssen Pharmaceutica in 1979.

Livocab direkt is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. Livocab direkt can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.

Livocab direkt
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Uses during Pregnancy
Uses during Breastfeeding
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Trade Name	Livocab direkt
Generic	Levocabastine
Levocabastine Other Names	Levocabastina, Levocabastine, Levocabastinum
Type
Formula	C₂₆H₂₉FN₂O₂
Weight	Average: 420.528 Monoisotopic: 420.221306345
Groups	Approved, Investigational
Therapeutic Class
Manufacturer
Available Country	Germany
Last Updated:	September 19, 2023 at 7:00 am

Uses

Livocab direkt is a selective histamine H1 receptor antagonist indicated for the management of seasonal allergic conjunctivitis symptoms.

As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.

Livocab direkt is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Conjunctivitis allergic

How Livocab direkt works

Livocab direkt is a potent, selective histamine H1-receptor antagonist. It works by competing with histamine for H1-receptor sites on effector cells. It thereby prevents, but does not reverse, responses mediated by histamine alone. Livocab direkt does not block histamine release but, rather, prevents histamine binding and activity. Livocab direkt also binds neurotensin 2 receptors and serves as a neurotensin agonist. This can induce some degree of analgesia.