livostin nasal

livostin nasal Uses, Dosage, Side Effects, Food Interaction and all others data.

livostin nasal is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. livostin nasal was discovered at Janssen Pharmaceutica in 1979.

livostin nasal is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. livostin nasal can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.

Trade Name livostin nasal
Generic Levocabastine
Levocabastine Other Names Levocabastina, Levocabastine, Levocabastinum
Weight 0.5mg/ml
Type Spray
Formula C26H29FN2O2
Weight Average: 420.528
Monoisotopic: 420.221306345
Groups Approved, Investigational
Therapeutic Class
Manufacturer Janssen Pharmaceutica N,v,
Available Country Saudi Arabia
Last Updated: September 19, 2023 at 7:00 am
livostin nasal
livostin nasal

Uses

livostin nasal is a selective histamine H1 receptor antagonist indicated for the management of seasonal allergic conjunctivitis symptoms.

As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.

livostin nasal is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Conjunctivitis allergic

How livostin nasal works

livostin nasal is a potent, selective histamine H1-receptor antagonist. It works by competing with histamine for H1-receptor sites on effector cells. It thereby prevents, but does not reverse, responses mediated by histamine alone. livostin nasal does not block histamine release but, rather, prevents histamine binding and activity. livostin nasal also binds neurotensin 2 receptors and serves as a neurotensin agonist. This can induce some degree of analgesia.

Toxicity

Adverse effects include visual disturbances, dry mouth, cough, nausea, eyelid edema and lacrimation.

Food Interaction

No interactions found.

Elimination Route

After instillation in the eye, levocabastine is systemically absorbed, albeit at low levels.

Half Life

36 hours (after oral administration)

Innovators Monograph

You find simplified version here livostin nasal

*** Taking medicines without doctor's advice can cause long-term problems.
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