Lofequik

Lofequik Uses, Dosage, Side Effects, Food Interaction and all others data.

Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.

Lornoxicam is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the oxicam class. As with other NSAIDS, lornoxicam is a potent inhibitor of the cyclooxgenase enzymes, which are responsible for catalyzing the formation of prostaglandins (act as messenger molecules in the process of inflammation) and thromboxane from arachidonic acid. Unlike some NSAIDS, lornoxicam's inhibition of cyclooxygenase does not lead to an increase in leukotriene formation, meaning that arachidonic acid is not moved to the 5-lipoxygenase cascade, resulting in the minimization of the risk of adverse events.

Trade Name Lofequik
Generic Lornoxicam + Paracetamol / Acetaminophen
Weight 8mg, 4mg
Type Tablet
Therapeutic Class
Manufacturer Sun Pharma
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Lofequik
Lofequik

Uses

Lornoxicam is an NSAID indicated in the treatment of mild to moderate pain, as well as rheumatoid arthritis and osteoarthritis.

For the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.

Lofequik is also used to associated treatment for these conditions: Osteoarthritis (OA), Rheumatoid Arthritis, Acute mild to moderate pain

How Lofequik works

Like other NSAIDS, lornoxicam's anti-inflammatory and analgesic activity is related to its inhibitory action on prostaglandin and thromboxane synthesis through the inhibition of both COX-1 and COX-2. This leads to the reduction of inflammation, pain, fever, and swelling, which are mediated by prostaglandins. However, the exact mechanism of lornoxicam, like that of the other NSAIDs, has not been fully determined.

Elimination Route

Lornoxicam is absorbed rapidly and almost completely from the GI tract (90-100%).

Half Life

3-5 hours

Innovators Monograph

You find simplified version here Lofequik


*** Taking medicines without doctor's advice can cause long-term problems.
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