Magacil Oral Suspension 400 mg/5 ml

Magacil Oral Suspension 400 mg/5 ml Uses, Dosage, Side Effects, Food Interaction and all others data.

Magacil Oral Suspension 400 mg/5 ml is a hydroxymagnesium aluminate complex that is converted rapidly in gastric acid to Mg(OH)2 and Al(OH)3, which are absorbed poorly and thus provide a sustained antacid effect

Table Of contents

• Magacil Oral Suspension 400 mg/5 ml
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Magacil Oral Suspension 400 mg/5 ml
Availability	Discontinued
Generic	Magaldrate
Magaldrate Other Names	Aluminium magnesium hydroxide sulfate hydrate, Aluminum magnesium hydroxide sulfate hydrate, Aluminum magnesium hydroxide sulphate hydrate, Hydrate magnesium aluminate activated sulfate, Magaldrate, Magaldrato, Magaldratum, Magnesium aluminate hydrate, Monalium hydrate
Related Drugs	omeprazole, famotidine, Pepcid, Prilosec, ranitidine, calcium carbonate
Weight	400 mg/5 ml
Type	Oral Suspension
Formula	Al5H33Mg10O40S2
Weight	Average: 1115.3 Monoisotopic: 1111.7570627
Groups	Approved, Withdrawn
Therapeutic Class	Antacids, Anti-dyspeptic/Carminatives
Manufacturer	Opsonin Pharma Ltd.
Available Country	Bangladesh
Last Updated:	October 19, 2023 at 6:27 am

Uses

Magacil Oral Suspension 400 mg/5 ml is used to relieve symptoms of dyspepsia, heartburn, acid indigestion, sour stomach, gastroesophageal reflux, hiatal hernia and flatulence. It is also prescribed in hyperacidity associated with peptic ulcers, gastritis and esophagitis. Magacil Oral Suspension 400 mg/5 ml may be given to children if necessary.

Magacil Oral Suspension 400 mg/5 ml is also used to associated treatment for these conditions: Acid indigestion, Aspiration, Bloating, Calcinosis, Dyspepsia, Gastroesophageal Reflux, Gastrointestinal Bleeding, Heartburn, Hyperacidity, Hyperparathyroidism, Kidney Stones, Peptic Ulcer, Stress Ulcers

Dosage

Magacil Oral Suspension 400 mg/5 ml dosage

Tablet: 1-3 tablets, after meals and at bed time or as directed by the physician.

Syrup: 2 to 3 teaspoonful, 3 or 4 times daily, half to one hour after or before meal and at bedtime

Side Effects

Constipation and diarrhea may occur.

Food Interaction

• Avoid alcohol.

Magacil Oral Suspension 400 mg/5 ml Drug Interaction

Moderate: rosuvastatinUnknown: amoxicillin / clavulanate, glucose, hydrochlorothiazide, pilocarpine ophthalmic, escitalopram, amlodipine, acetaminophen, tiotropium, diltiazem

Magacil Oral Suspension 400 mg/5 ml Disease Interaction

Major: constipation, renal dysfunctionModerate: diarrhea

Elimination Route

Aluminium oxide: absorbed Al ions are eliminated in the urine (0.1-0.5 mg of Al in aluminium-containing antacid is absorbed from standard daily doses of antacid) while insoluble or poorly absorbed Al salts in the intestines are excreted through the feces.

Magnesium oxide: absorbed Mg ions (up to 30%) are eliminated in the urine, unabsorbed is excreted in the feces.

Pregnancy & Breastfeeding use

Pregnant women: Magacil Oral Suspension 400 mg/5 ml may be used in pregnancy if indicated however one should avoid excessive dosage.

Lactating mother: Magacil Oral Suspension 400 mg/5 ml may pass into breast milk but has not been reported to cause problem in nursing babies.

Contraindication

Magacil Oral Suspension 400 mg/5 ml is contraindicated in patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal function

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