Manitimus
Manitimus Uses, Dosage, Side Effects, Food Interaction and all others data.
FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy.
Trade Name | Manitimus |
Generic | Manitimus |
Manitimus Other Names | Manitimus |
Type | |
Formula | C15H11F3N2O2 |
Weight | Average: 308.26 Monoisotopic: 308.077262091 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in immunosuppressive and transplant (rejection).
How Manitimus works
FK778 exerts its immunosuppressive activity at the molecular level via the suppression of de-novo pyrimidine biosynthesis, inhibiting the action of dihydroorotate dehydrogenase, an enzyme critical in the process, and consequently inhibiting cell proliferation.
Innovators Monograph
You find simplified version here Manitimus