Manitimus Uses, Dosage, Side Effects and more
FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy.
| Trade Name | Manitimus |
| Generic | Manitimus |
| Manitimus Other Names | Manitimus |
| Type | |
| Formula | C15H11F3N2O2 |
| Weight | Average: 308.26 Monoisotopic: 308.077262091 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in immunosuppressive and transplant (rejection).
How Manitimus works
FK778 exerts its immunosuppressive activity at the molecular level via the suppression of de-novo pyrimidine biosynthesis, inhibiting the action of dihydroorotate dehydrogenase, an enzyme critical in the process, and consequently inhibiting cell proliferation.
