Marileon N

Marileon N Uses, Dosage, Side Effects, Food Interaction and all others data.

An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.

Marileon N is a potent vasodilator (improves brain blood flow). On the cerebral level it prompts a lowering of vascular resistance, an increase in arterial flow and stimulates the use of oxygen and glucose. Marileon N also improves blood circulation in the lungs and limbs and has been shown to inhibit blood platelet aggregation.

Trade Name Marileon N
Generic Nicergoline
Nicergoline Other Names Nicergolin, Nicergolina, Nicergoline, Nicergolinum
Type
Formula C24H26BrN3O3
Weight Average: 484.386
Monoisotopic: 483.11575436
Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country Japan
Last Updated: September 19, 2023 at 7:00 am
Marileon N
Marileon N

Uses

Marileon N is an ergot derivative use for the treatment of symptoms associated with cerebrovascular abnormalities.

For the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration.

Marileon N is also used to associated treatment for these conditions: Stroke, Ischemic, Transient Ischemic Attack, Peripheral vasodilatation

How Marileon N works

Marileon N acts by inhibiting the postsynaptic alpha(1)-adrenoceptors on vascular smooth muscle. This inhibits the vasoconstrictor effect of circulating and locally released catecholamines (epinephrine and norepinephrine), resulting in peripheral vasodilation. Therefore the mechanism of Marileon N is to increase vascular circulation in the brain, thereby enhancing the transmission of nerve signals across the nerve fibres, which secrete acetylcholine as a neural transmitter.

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*** Taking medicines without doctor's advice can cause long-term problems.
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