Masti-Safe

Masti-Safe Uses, Dosage, Side Effects, Food Interaction and all others data.

Masti-Safe (INN, also spelled cephapirin), commonly marketed under the trade name Cefadyl, is a first-generation cephalosporin antibiotic that is available in injectable formulations. Production for use in humans has been discontinued in the United States. Masti-Safe is partly plasma-bound and is effective against gram-negative and gram-positive organisms.

Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.

Table Of contents

• Masti-Safe
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Masti-Safe
Generic	Cefapirin
Cefapirin Other Names	Cefapirin, Cefapirina, Cefapirine, Cefapirinum, Cefaprin, Cephapirin, Cephapirine
Type
Formula	C17H17N3O6S2
Weight	Average: 423.463 Monoisotopic: 423.055876671
Groups	Approved, Vet approved
Therapeutic Class
Manufacturer
Available Country	Germany
Last Updated:	September 19, 2023 at 7:00 am

Uses

Masti-Safe is a first generation cephalosporin indicated in the treatment of susceptible bacterial infections.

For treatment of infections caused by susceptible bacteria.

Masti-Safe is also used to associated treatment for these conditions: Bronchitis, Pharyngitis, Respiratory Tract Infections (RTI), Skin and Soft Tissue Infections, Tonsillitis, Urinary Tract Infection

How Masti-Safe works

The bactericidal activity of cephapirin results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).

Toxicity

Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD₅₀ = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.

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