Mebaral Uses, Dosage, Side Effects and more

Trade Name Mebaral
Availability Discontinued
Generic Mephobarbital
Related Drugs gabapentin, trazodone, hydroxyzine, clonazepam, lorazepam, lamotrigine, diazepam, pregabalin, Lyrica, topiramate
Type Tablet
Therapeutic Class
Manufacturer
Available Country United States
Last Updated: January 7, 2025 at 1:49 am

Mebaral Alcohol interaction

[Major] GENERALLY AVOID:

Concurrent acute use of barbiturates and ethanol may result in additive CNS effects,

including impaired coordination, sedation, and death.

Tolerance of these agents may occur with chronic use.

The mechanism is related to inhibition of microsomal enzymes acutely and induction of hepatic microsomal enzymes chronically.



The combination of ethanol and barbiturates should be avoided.

Drug Interaction

Moderate: atorvastatin, atorvastatin, diazepam, diazepamUnknown: zinc sulfate, zinc sulfate

Disease Interaction

Major: acute alcohol intoxication, drug dependence, liver disease, porphyria, rash, respiratory depression, renal dysfunctionModerate: suicidal tendency, adrenal insufficiency, depression, hematologic toxicity, osteomalacia, paradoxical reactions

Innovators Monograph


*** Taking medicines without doctor's advice can cause long-term problems.
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