Mebeverine HCl Retard
Mebeverine HCl Retard Uses, Dosage, Side Effects, Food Interaction and all others data.
Mebeverine HCl Retard is a musculotropic antispasmodic agent used to relieve cramps or spasms of the stomach and intestine (gut). It is particularly useful in treating Irritable Bowel Syndrome (IBS) and similar conditions. It works by relaxing the muscles and helping to restore the normal movement of the gut.
| Trade Name | Mebeverine HCl Retard |
| Generic | Mebeverine |
| Mebeverine Other Names | Mebeverina, Mebeverine, Mebeverinum |
| Type | |
| Formula | C25H35NO5 |
| Weight | Average: 429.557 Monoisotopic: 429.251523231 |
| Groups | Approved, Investigational |
| Therapeutic Class | Anticholinergics |
| Manufacturer | |
| Available Country | Netherlands |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the symptomatic treatment of Irritable Bowel Syndrome (IBS) and other conditions include:
- Chronic irritable colon
- Spastic constipation
- Mucous colitis
- Colicky abdominal pain
- Persistent non-specific diarrhea
Mebeverine HCl Retard is also used to associated treatment for these conditions: Abdominal Pain, Abdominal Spasms, Abnormal Bowel Movement Such as Constipation, Diarrhea, Abdominal Pain, Irritable Bowel Syndrome (IBS), Bowel discomfort
Dosage
Mebeverine HCl Retard dosage
135 mg tid, may reduce gradually after several wk when the desired effect has been obtained; 100 mg tid has also been used. As modified-release cap: 200 mg bid.
Mebeverine HCl Retard is most effective when taken 20 minutes before meals. After several weeks when the desired effect has been obtained, the dosage may be gradually reduced.
Missed dose: If a dose of this medicine is missed, that should be taken as soon as possible. However, if it is almost time for the next dose, then skip the missed dose and the regular dosing schedule should be maintained. Dose should not be doubled at the same time to compensate the missed dose.
Side Effects
Generally Mebeverine HCl Retard is well tolerated. However, few side-effects like skin rash, urticaria and angioedema may appear.
Precaution
Caution should be exercised in porphyria or allergic reaction to this or any other medicine of this group.
Food Interaction
No interactions found.Pregnancy & Breastfeeding use
No teratogenicity has been shown in animal experiments. However, the usual precautions concerning the administration of any drug during pregnancy should be exercised. Mebeverine HCl Retard does not excrete in the breast milk after administering the therapeutic dose.
Special Warning
Use in children: Mebeverine HCl Retard is not recommended in children under 10 years.
Acute Overdose
Symptoms: CNS excitability
Management: Symptomatic and supportive treatment. Gastric lavage may be considered in case of multiple intoxication or if discovered w/in approx 1 hr.
Storage Condition
Store below 30° C.
Innovators Monograph
You find simplified version here Mebeverine HCl Retard
Mebeverine HCl Retard contains Mebeverine see full prescribing information from innovator Mebeverine HCl Retard Monograph, Mebeverine HCl Retard MSDS, Mebeverine HCl Retard FDA label
FAQ
What is Mebeverine HCl Retard used for?
Mebeverine HCl Retard helps with muscle spasms. It can be used to ease painful stomach cramps if you have irritable bowel syndrome (IBS) or other conditions.
How safe is Mebeverine HCl Retard?
Mebeverine HCl Retard is generally safe and you're unlikely to have side effects. Some people may get an itchy rash (hives).
How does Mebeverine HCl Retard work?
Mebeverine HCl Retard works by relaxing the muscles in your intestine. This relieves the cramps and pain that can be caused by IBS or other conditions.
What are the common side effects of Mebeverine HCl Retard?
The common side effects of Mebeverine HCl Retard are:
- Nausea.
- Vomiting.
- Rash.
- Headache.
- Heartburn.
- Indigestion.
- Constipation.
- Dizziness.
Is Mebeverine HCl Retard safe during pregnancy?
Mebeverine HCl Retard are not recommended during pregnancy.
Is Mebeverine HCl Retard safe during breastfeeding?
It is usually safe to breastfeed while taking Mebeverine HCl Retard. Some of the medicine may pass into your breast milk. However, this is in small amounts and unlikely to harm your baby.
Can I drink alcohol with Mebeverine HCl Retard?
Yes, you can drink alcohol with Mebeverine HCl Retard.
When should be best taken of Mebeverine HCl Retard?
It's best to take your Mebeverine HCl Retard 20 minutes before a meal.
How often can I take Mebeverine HCl Retard?
The recommended dose is one tablet three times a day. Do not take more than three tablets per day.
Can I Mebeverine HCl Retard take on an empty stomach?
Mebeverine HCl Retard should take on an empty stomach. If you take it twice a day, take it before breakfast and dinner. If you take it 3 times a day, take it before breakfast, lunch and dinner.
How long does Mebeverine HCl Retard take to work?
Mebeverine HCl Retard starts to work after 1 hour. You should feel better 1 to 3 hours after taking it.
What is the half life of Mebeverine HCl Retard?
The steady state elimination half-life of DMAC is 2.45 h.
Does Mebeverine HCl Retard raise blood pressure?
Mebeverine HCl Retard also significantly reduced heart rate and arterial blood pressure.
Can I take Mebeverine HCl Retard for a long time?
You will usually only take Mebeverine HCl Retard if you are having a flare-up of your IBS symptoms.
Who should not take Mebeverine HCl Retard?
The recommended dose is one tablet three times a day. Do not take more than three tablets per day. The number of tablets you take may be lowered if your symptoms improve. Children and adolescents: Mebeverine HCl Retard is not recommended for use in children and adolescents below 18 years of age.
What happen If I missed Mebeverine HCl Retard?
If you miss a dose of Mebeverine HCl Retard, skip the missed dose and take the next one as usual. Do not take a double dose to make up for a missed dose. If you forget doses often, it may help to set an alarm to remind you.
What happens if I take too much Mebeverine HCl Retard?
If you take too much Mebeverine HCl Retard by accident, it is unlikely to harm you. Speak to a pharmacist or doctor if you're worried.
Can I just stop taking Mebeverine HCl Retard?
You can stop taking Mebeverine HCl Retard when you feel better. This may take up to 2 weeks. If you do not get better within 2 weeks of taking Mebeverine HCl Retard, or get worse at any time, talk to a doctor.
Does Mebeverine HCl Retard raise blood pressure?
Mebeverine HCl Retard also significantly reduced heart rate and arterial blood pressure.
Does Mebeverine HCl Retard cause tachycardia?
Transient bradycardia followed by tachycardia.
