Mebghol

Mebghol Uses, Dosage, Side Effects, Food Interaction and all others data.

Mebeverine is a musculotropic antispasmodic agent used to relieve cramps or spasms of the stomach and intestine (gut). It is particularly useful in treating Irritable Bowel Syndrome (IBS) and similar conditions. It works by relaxing the muscles and helping to restore the normal movement of the gut.

Each spoonful contains 3.5 gm Psyllium husk as an active ingredient. When the husk is mixed with water it forms a thick gel that helps to relieve constipation & regularize bowel.Psyllium Husk is a mild laxative & it contains 80% soluble fibre. The main chemical ingredient of Psyllium is mucilage; very useful in chronic constipation, piles or hemorrhoids & colon cancer. It has also soothing effects on the gastric & intestinal mucosa and hence effective in gastric irritation and ulceration. Psyllium also lowers serum cholesterol levels (LDL), reduces blood glucose that are suitable for obese & diabetic patients.

Mebghol
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Mebghol
Generic	Mebeverine + Psyllium Husk
Weight	135mg, 3.5mg
Type	Sachet
Therapeutic Class
Manufacturer	Warafana Pharmaceuticals
Available Country	Pakistan
Last Updated:	September 19, 2023 at 7:00 am

Uses

For the symptomatic treatment of Irritable Bowel Syndrome (IBS) and other conditions include:

Chronic irritable colon
Spastic constipation
Mucous colitis
Colicky abdominal pain
Persistent non-specific diarrhea

Psyllium Husk is used for-

Constipation
Raised levels of cholesterol
Hemorrhoids or piles
Irritable bowel syndrome (IBS)
Reduces blood glucose level

Psyllium also provides easy bowel movement with smooth stool. So, it is desirable in patients with anal fissures, colon cancer, post anal & rectal surgery and during pregnancy.

Mebghol is also used to associated treatment for these conditions: Abdominal Pain, Abdominal Spasms, Abnormal Bowel Movement Such as Constipation, Diarrhea, Abdominal Pain, Irritable Bowel Syndrome (IBS), Bowel discomfort

Dosage

Mebghol dosage

135 mg tid, may reduce gradually after several wk when the desired effect has been obtained; 100 mg tid has also been used. As modified-release cap: 200 mg bid.

Usual dose: 1 spoonful 1-3 times daily or as per doctor's advice.

Adults and children over 12 years: 1 spoonful with water 2 times daily or as per doctor's advice.

Children 6 to 12 years: ½ to 1 spoonful with water depending on age and size, in the morning and at bedtime or as per doctor's advice.

Children below 6 years: Not recommended except as directed by the physician.

An additional glass of water is helpful after taking this gel.

Mebeverine is most effective when taken 20 minutes before meals. After several weeks when the desired effect has been obtained, the dosage may be gradually reduced.

Missed dose: If a dose of this medicine is missed, that should be taken as soon as possible. However, if it is almost time for the next dose, then skip the missed dose and the regular dosing schedule should be maintained. Dose should not be doubled at the same time to compensate the missed dose.

Take one spoonful with the provided spoon.
Put this husk into an empty glass.
Fill glass with water (150 ml or 2/3 of the glass) stir & drink immediately.

Side Effects

Generally Mebeverine is well tolerated. However, few side-effects like skin rash, urticaria and angioedema may appear.

Common side effects are flatulence, abdominal distension, gastro-intestinal obstruction.

Precaution

Caution should be exercised in porphyria or allergic reaction to this or any other medicine of this group.

Interaction

No significant interaction has been observed with other medicine.

Pregnancy & Breastfeeding use

No teratogenicity has been shown in animal experiments. However, the usual precautions concerning the administration of any drug during pregnancy should be exercised. Mebeverine does not excrete in the breast milk after administering the therapeutic dose.

Contraindication

Contraindicated in patients with gastrointestinal tract obstruction or threatening obstruction of the bowel.

Special Warning

Use in children: Mebeverine is not recommended in children under 10 years.

Acute Overdose

Symptoms: CNS excitability

Management: Symptomatic and supportive treatment. Gastric lavage may be considered in case of multiple intoxication or if discovered w/in approx 1 hr.